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福建省单中心器官捐献转化率和器官产出率及其影响因素研究

谢贤宇 吴勤德 杨慧杰 魏琴 吴勇 张蕙

谢贤宇, 吴勤德, 杨慧杰, 等. 福建省单中心器官捐献转化率和器官产出率及其影响因素研究[J]. 器官移植, 2022, 13(1): 98-104. doi: 10.3969/j.issn.1674-7445.2022.01.015
引用本文: 谢贤宇, 吴勤德, 杨慧杰, 等. 福建省单中心器官捐献转化率和器官产出率及其影响因素研究[J]. 器官移植, 2022, 13(1): 98-104. doi: 10.3969/j.issn.1674-7445.2022.01.015
Xie Xianyu, Wu Qinde, Yang Huijie, et al. Analysis of conversion rate, organ procurement rate and influencing factors of organ donation: a single-center study in Fujian province[J]. ORGAN TRANSPLANTATION, 2022, 13(1): 98-104. doi: 10.3969/j.issn.1674-7445.2022.01.015
Citation: Xie Xianyu, Wu Qinde, Yang Huijie, et al. Analysis of conversion rate, organ procurement rate and influencing factors of organ donation: a single-center study in Fujian province[J]. ORGAN TRANSPLANTATION, 2022, 13(1): 98-104. doi: 10.3969/j.issn.1674-7445.2022.01.015

福建省单中心器官捐献转化率和器官产出率及其影响因素研究

doi: 10.3969/j.issn.1674-7445.2022.01.015
基金项目: 

福建省财政专项基金项目 2020CZ001

详细信息
    作者简介:

    谢贤宇,男,1991年生,硕士,助理研究员,研究方向为卫生经济管理、器官捐献与移植管理,Email: 1019327388@qq.com

    通讯作者:

    魏琴,女,1983年生,硕士,副研究员,硕士研究生导师,研究方向为医疗管理、器官捐献与移植管理、公共卫生,Email:simony2004@126.com

  • 中图分类号: R617, R19

Analysis of conversion rate, organ procurement rate and influencing factors of organ donation: a single-center study in Fujian province

More Information
  • 摘要:   目的  探讨福建省单中心器官捐献转化率和器官产出率及其影响因素。  方法  回顾性分析2018年11月至2021年6月福建医科大学附属协和医院182例潜在器官捐献者的基本信息,分析器官捐献转化率、器官捐献成功者的基本情况及器官捐献失败者捐献失败的原因。分析器官捐献产出情况及器官捐献数量的影响因素。  结果  182例潜在器官捐献者中,捐献成功46例,捐献转化率为25.3%;失败136例,失败原因包括家属不同意(58.1%)、无充足时间评估(24.3%)和未达到捐献状态标准(17.6%)。46例器官捐献者共捐献大器官和组织212个,包括肾脏88个、肝脏42个、肺脏15个、心脏19个和角膜48个,人均捐献大器官和组织4.6个,人均捐献大器官3.6个。年龄、性别、籍贯、捐献辖区和血型是大器官捐献数量的影响因素;捐献辖区是组织捐献数量的影响因素。  结论  福建省单中心器官捐献转化率偏低,家属不同意是最主要的原因。应针对性地选择合适的潜在器官捐献者开展器官捐献工作,提升器官捐献转化率和器官产出率。

     

  • 表  1  2018年11月至2021年6月福建医科大学附属协和医院器官捐献的产出情况

    Table  1.   Output of organ donation in Fujian Medical University Union Hospital from November 2018 to June 2021

    年度 完成器官捐献例数(例) 获取器官个数(个) 获取组织个数(个)
    DBD DCD 合计 心脏 肺脏 肝脏 肾脏 合计 角膜
    2018 1 0 1 1 0 0 2 3 0
    2019 13 0 13 8 1 13 24 46 14
    2020 14 4 18 8 14 16 34 72 24
    2021 12 2 14 2 0 13 28 43 10
    合计 40 6 46 19 15 42 88 164 48
    注:①为脑死亡器官捐献。
           ②为心脏死亡器官捐献。
    下载: 导出CSV

    表  2  2018年11月至2021年6月福建医科大学附属协和医院器官捐献成功者的器官捐献情况

    Table  2.   Organ donation information of successful organ donors in Fujian Medical University Union Hospital from November 2018 to June 2021 [M(P25, P75)]

    指标 n 大器官捐献个数 统计值 P 组织捐献个数 统计值 P
    年龄 16.681 0.001 1.460 0.692
      0~19岁 3 4(4, 5) 2(1, 2)
      20~49岁 29 4(3, 4) 1(0, 2)
      50~64岁 12 3(3, 4) 1(0, 2)
      ≥65岁 2 3(3, 3) 2(2, 2)
    性别 −2.438 0.015 −0.825 0.409
      男 33 3(3, 4) 2(0, 2)
      女 13 3(3, 3) 0(0, 2)
    籍贯 −5.175 < 0.001 −1.011 0.312
      福建省内 29 4(3, 4) 2(0, 2)
      外省 17 3(3, 3) 0(0, 2)
    捐献辖区 10.765 0.005 6.130 0.047
      福州 16 4(3, 4) 2(0, 2)
      宁德 12 3(3, 4) 1(0, 2)
      南平 18 3(3, 4) 0(0, 2)
    血型 8.455 0.037 2.415 0.491
      A型 19 3(3, 4) 2(0, 2)
      B型 7 3(3, 4) 0(0, 1)
      AB型 2 4(3, 5) 1(0, 2)
      O型 18 4(3, 4) 2(0, 2)
    BMI 5.380 0.068 1.226 0.542
       < 18.5 kg/m2 2 3(3, 3) 1(0, 2)
      18.5~24.0 kg/m2 31 3(3, 4) 1(0, 2)
       > 24.0 kg/m2 13 3(3, 4) 2(0, 2)
    死亡原因 0.990 0.610 2.043 0.360
      脑外伤 29 3(3, 4) 0(0, 2)
      脑卒中 11 3(3, 4) 2(0, 2)
      其他 6 4(3, 4) 2(2, 2)
    捐献类型 −0.416 0.678 −1.852 0.064
      DBD 40 3(3, 4) 2(0, 2)
      DCD 6 3(3, 4) 1(0, 2)
    注:①包括心脏、肝脏、肾脏、肺脏。
           ②指角膜。
           ③为脑死亡器官捐献。
           ④为心脏死亡器官捐献。
    下载: 导出CSV
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  • 收稿日期:  2021-08-16
  • 网络出版日期:  2022-01-12
  • 刊出日期:  2022-01-15

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