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三维斑点追踪成像技术定量评价肾移植受者术后左心室整体应变

唐君仪 隋明星 奚佳颖 朱霞玲 蔡珠虹 金修才

唐君仪, 隋明星, 奚佳颖, 等. 三维斑点追踪成像技术定量评价肾移植受者术后左心室整体应变[J]. 器官移植, 2021, 12(4): 458-464. doi: 10.3969/j.issn.1674-7445.2021.04.013
引用本文: 唐君仪, 隋明星, 奚佳颖, 等. 三维斑点追踪成像技术定量评价肾移植受者术后左心室整体应变[J]. 器官移植, 2021, 12(4): 458-464. doi: 10.3969/j.issn.1674-7445.2021.04.013
Tang Junyi, Sui Mingxing, Xi Jiaying, et al. Three-dimensional speckle tracking imaging for quantitative evaluation of left ventricular global strain in renal transplant recipients[J]. ORGAN TRANSPLANTATION, 2021, 12(4): 458-464. doi: 10.3969/j.issn.1674-7445.2021.04.013
Citation: Tang Junyi, Sui Mingxing, Xi Jiaying, et al. Three-dimensional speckle tracking imaging for quantitative evaluation of left ventricular global strain in renal transplant recipients[J]. ORGAN TRANSPLANTATION, 2021, 12(4): 458-464. doi: 10.3969/j.issn.1674-7445.2021.04.013

三维斑点追踪成像技术定量评价肾移植受者术后左心室整体应变

doi: 10.3969/j.issn.1674-7445.2021.04.013
基金项目: 

上海市科学技术委员会科研计划项目 19ZR1478200

详细信息
    作者简介:

    唐君仪,女,1992年生,硕士,医师,研究方向为心血管超声,Email: tangjy2010@sina.com

    通讯作者:

    金修才,男,1971年生,博士,副主任医师,研究方向为心血管超声,Email: goldenxc@126.com

  • 中图分类号: R617, R540.4+5

Three-dimensional speckle tracking imaging for quantitative evaluation of left ventricular global strain in renal transplant recipients

More Information
  • 摘要:   目的  探讨采用三维斑点追踪成像(3D-STI)技术定量评价肾移植受者术后3个月内左心室整体应变的应用价值。  方法  选取34例肾移植受者,分别于术前、术后7 d、术后1个月、术后3个月收集受者的血压、血清肌酐和他克莫司血药浓度等资料,同时对受者行常规超声心动图和3D-STI检查,收集受者超声心动图检查参数[左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)、左心室射血分数(LVEF)]和3D-STI检查参数[左心室整体纵向峰值应变(GPLS)、整体圆周峰值应变(GPCS)、整体径向峰值应变(GPRS)及整体面积峰值应变(GPAS)]。比较受者术前、术后7 d、术后1个月、术后3个月上述指标的变化,分析应用3D-STI技术定量评价肾移植受者术后3个月内左心室整体应变的变化特点及其应用价值。  结果  肾移植受者术前至术后3个月内各时间点间LVEF和GPCS比较,差异均无统计学意义(均为P > 0.05)。术前至术后3个月内各时间点间LVEDV、LVESV、GPLS、GPAS和GPRS比较,差异均有统计学意义(均为P < 0.001)。GPLS、GPAS、GPRS在术后1个月内呈连续下降趋势,术后3个月有所上升但仍低于术前水平。  结论  应用3D-STI技术能够敏感地发现肾移植受者术后LVEF未见明显改变时左心室整体应变的改变,与常规超声心动图比较,3D-STI可以更准确地评价肾移植受者术后左心室整体应变的变化特点。

     

  • 图  1  1例受者肾移植术前、术后左心室GPLS曲线

    注:A、B、C、D图分别为肾移植受者术前、术后7 d、术后1个月、术后3个月的左心室GPLS曲线。

    Figure  1.  The GPLS curves of a recipient before and after renal transplantation

    表  1  肾移植术前、术后受者一般情况比较

    Table  1.   Comparison of general conditions of recipients before and after renal transplantation(x±s)

    检查时间 n 收缩压(mmHg 舒张压(mmHg) 血清肌酐(μmol/L) 他克莫司血药浓度(ng/mL)
    术前 34 143±14 91±9 1 008±389 -
    术后7 d 34 136±13 87±10 189±75a 13.6±3.4
    术后1个月 34 130±8a, b 83±8a 147±42a, b 14.8±3.0
    术后3个月 34 128±6a, b 80±6a, b 137±20a, b 9.8±1.6b, c
    P < 0.001 < 0.001 < 0.001 < 0.001
    注:与术前比较,aP < 0.05/6;与术后7 d比较,bP < 0.05/6;与术后1个月比较,cP < 0.05/6。
    ①1 mmHg=0.133 kPa。
    ②-为无数据。
    下载: 导出CSV

    表  2  肾移植术前、术后受者常规超声心动图检查结果比较

    Table  2.   Comparison of conventional echocardiography results in recipients before and after renal transplantation(x±s)

    检查时间 n LVEDV(mL) LVESV(mL) LVEF(%)
    术前 34 101±23 46±12 55±5
    术后7 d 34 96±24 a 42±11 a 55±4
    术后1个月 34 88±18 a, b 38±9 a, b 56±5
    术后3个月 34 83±14 a, b 36±9 a, b 57±6
    P < 0.001 < 0.001 0.199
    注:与术前比较,aP < 0.05/6;与术后7 d比较,bP < 0.05/6。
    下载: 导出CSV

    表  3  肾移植术前、术后受者3D-STI检查结果比较

    Table  3.   Comparison of 3D-STI examination results in recipients before and after renal transplantation(x±s, %)

    检查时间 n GPLS GPCS GPAS GPRS
    术前 34 10.3±2.2 12.5±3.2 21±5 29±8
    术后7 d 34 8.8±2.1a 12.9±2.8 20±4 a 27±7a
    术后1个月 34 7.9±2.1a, b 11.5±3.2 18±4a, b 24±7a, b
    术后3个月 34 9.6±2.2a, b, c 12.6±2.7 20±4c 28±6c
    P < 0.001 0.121 < 0.001 < 0.001
    注:与术前比较,aP < 0.05/6;与术后7 d比较,bP < 0.05/6;与术后1个月比较,cP < 0.05/6。
    下载: 导出CSV

    表  4  3D-STI检查的可重复性检测

    Table  4.   Repeatability test of 3D-STI examination(x±s, %)

    测量顺序 n GPLS GPCS GPAS GPRS
    第1次 10 10.5±1.4 12.2±2.1 20.1±2.5 28±5
    第2次 10 10.6±1.4 12.1±3.2 20.5±3.2 28±6
    P 0.90 0.85 0.45 0.74
    下载: 导出CSV
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出版历程
  • 收稿日期:  2021-04-30
  • 网络出版日期:  2021-07-13
  • 刊出日期:  2021-07-15

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