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胰岛类器官基础应用的研究现状与展望

吴玲玲 蒋鹏 武桢 李万里 杨玉伟 高宏君

吴玲玲, 蒋鹏, 武桢, 等. 胰岛类器官基础应用的研究现状与展望[J]. 器官移植, 2021, 12(4): 397-402. doi: 10.3969/j.issn.1674-7445.2021.04.005
引用本文: 吴玲玲, 蒋鹏, 武桢, 等. 胰岛类器官基础应用的研究现状与展望[J]. 器官移植, 2021, 12(4): 397-402. doi: 10.3969/j.issn.1674-7445.2021.04.005
Wu Lingling, Jiang Peng, Wu Zhen, et al. Research status and prospect of basic application of islet organoid[J]. ORGAN TRANSPLANTATION, 2021, 12(4): 397-402. doi: 10.3969/j.issn.1674-7445.2021.04.005
Citation: Wu Lingling, Jiang Peng, Wu Zhen, et al. Research status and prospect of basic application of islet organoid[J]. ORGAN TRANSPLANTATION, 2021, 12(4): 397-402. doi: 10.3969/j.issn.1674-7445.2021.04.005

胰岛类器官基础应用的研究现状与展望

doi: 10.3969/j.issn.1674-7445.2021.04.005
基金项目: 

广西自然科学基金 2020GXNSFAA238024

广西中医药大学研究生教育创新计划项目 YCSW2021232

详细信息
    作者简介:

    吴玲玲,女,1995年生,硕士研究生,研究方向为器官移植,Email:2111572399@qq.com

    通讯作者:

    高宏君,男,1964年生,博士,主任医师,研究方向为器官移植,Email:gao4056@163.com

  • 中图分类号: R617, R587

Research status and prospect of basic application of islet organoid

More Information
  • 摘要: 类器官指利用干细胞的全能性,将其在体外进行培养,使其不断进行自我更新和自我组织,形成结构和功能与原始器官相似的组织。类器官具有与原始组织保持相似外观和功能的特点,已广泛应用于基础研究及临床研究。目前已经成功培养出肝、肾、胰、脑、肠等类器官,其中使用胰岛类器官是类器官领域研究的热点,但由于还未完全解决移植术后排斥反应等问题,目前胰岛类器官仅用于基础研究。本文对胰岛类器官的起源与发展、胰岛类器官的基础应用进行综述,旨在为胰岛类器官实现基础应用向临床应用转化及糖尿病的治疗提供参考。

     

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出版历程
  • 收稿日期:  2021-03-01
  • 网络出版日期:  2021-07-13
  • 刊出日期:  2021-07-15

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