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葫芦巴碱调节肾移植术后代谢紊乱的应用前景

黎忠大 刘东 王晓 庄锦炀

黎忠大, 刘东, 王晓, 等. 葫芦巴碱调节肾移植术后代谢紊乱的应用前景[J]. 器官移植, 2021, 12(3): 363-368. doi: 10.3969/j.issn.1674-7445.2021.03.017
引用本文: 黎忠大, 刘东, 王晓, 等. 葫芦巴碱调节肾移植术后代谢紊乱的应用前景[J]. 器官移植, 2021, 12(3): 363-368. doi: 10.3969/j.issn.1674-7445.2021.03.017
Li Zhongda, Liu Dong, Wang Xiao, et al. Application prospects of trigonelline in regulating metabolic disorders after renal transplantation[J]. ORGAN TRANSPLANTATION, 2021, 12(3): 363-368. doi: 10.3969/j.issn.1674-7445.2021.03.017
Citation: Li Zhongda, Liu Dong, Wang Xiao, et al. Application prospects of trigonelline in regulating metabolic disorders after renal transplantation[J]. ORGAN TRANSPLANTATION, 2021, 12(3): 363-368. doi: 10.3969/j.issn.1674-7445.2021.03.017

葫芦巴碱调节肾移植术后代谢紊乱的应用前景

doi: 10.3969/j.issn.1674-7445.2021.03.017
基金项目: 

广东省医学科研基金 A2020371

广州市科技计划项目 201804010421

详细信息
    作者简介:

    黎忠大,男,硕士研究生,研究方向为泌尿外科,Email: LZD13590024576@163.com

    通讯作者:

    刘东,男,博士,主任医师,研究方向为泌尿外科及器官移植,Email: ld177@163.com

  • 中图分类号: R617, R589

Application prospects of trigonelline in regulating metabolic disorders after renal transplantation

More Information
  • 摘要: 肾移植术后易发生糖、脂质等代谢紊乱,导致移植肾功能障碍及长期存活率降低。葫芦巴碱是一种具有多种生物活性的天然生物碱,具有改善糖、脂质等代谢紊乱的作用,可减轻肾脏的炎症反应、氧化应激及细胞凋亡,从而保护肾功能。因此,葫芦巴碱可能是调节肾移植术后代谢紊乱的潜在药物。本文对葫芦巴碱与糖代谢紊乱、脂质代谢紊乱、其他代谢紊乱及葫芦巴碱在肾移植中的应用前景进行综述,旨在为改善肾移植术后代谢紊乱、提高肾移植受者及移植肾的长期存活率提供参考。

     

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出版历程
  • 收稿日期:  2021-02-21
  • 网络出版日期:  2021-05-19
  • 刊出日期:  2021-05-15

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