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公民逝世后器官捐献供肾损伤相关分子标志物的研究进展

韩飞 孙启全

韩飞, 孙启全. 公民逝世后器官捐献供肾损伤相关分子标志物的研究进展[J]. 器官移植, 2020, 11(4): 526-532. doi: 10.3969/j.issn.1674-7445.2020.04.018
引用本文: 韩飞, 孙启全. 公民逝世后器官捐献供肾损伤相关分子标志物的研究进展[J]. 器官移植, 2020, 11(4): 526-532. doi: 10.3969/j.issn.1674-7445.2020.04.018
Han Fei, Sun Qiquan. Research progress on molecular markers related to the donor kidney injury from organ donation after citizen's death[J]. ORGAN TRANSPLANTATION, 2020, 11(4): 526-532. doi: 10.3969/j.issn.1674-7445.2020.04.018
Citation: Han Fei, Sun Qiquan. Research progress on molecular markers related to the donor kidney injury from organ donation after citizen's death[J]. ORGAN TRANSPLANTATION, 2020, 11(4): 526-532. doi: 10.3969/j.issn.1674-7445.2020.04.018

公民逝世后器官捐献供肾损伤相关分子标志物的研究进展

doi: 10.3969/j.issn.1674-7445.2020.04.018
基金项目: 

国家自然科学基金 81970650

国家自然科学基金青年基金项目 81800661

详细信息
    作者简介:

    韩飞,男,1992年,博士,研究方向为供肾功能评估,Email: hanfei110033@163.com

    通讯作者:

    孙启全,男,1973年,博士,主任医师,研究方向为肾移植相关疾病,Email: sunqiq@mail.sysu.edu.cn

  • 中图分类号: R617

Research progress on molecular markers related to the donor kidney injury from organ donation after citizen's death

More Information
  • 摘要: 供肾短缺是肾移植面临的一大难题,对供肾功能的准确评估可以降低器官的弃用率,以挽救更多的尿毒症患者。与病理学检查相比,循环中的分子标志物检测在临床应用中较为方便。本文就目前已发现的肾损伤标志物血清肌酐和血清胱抑素C(Cys-C)、中性粒细胞明胶酶相关脂质运载蛋白(NGAL)、肝型脂肪酸结合蛋白(L-FABP)、线粒体DNA(mtDNA)、肾损伤分子-1(KIM-1)和白细胞介素-18(IL-18)等方面的研究进展进行简要介绍。

     

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出版历程
  • 收稿日期:  2020-04-26
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2020-07-15

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