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Klotho:一个潜在的移植肾保护蛋白

庄锦炀 刘东 邓庚国 王晓

庄锦炀, 刘东, 邓庚国, 等. Klotho:一个潜在的移植肾保护蛋白[J]. 器官移植, 2020, 11(4): 508-515. doi: 10.3969/j.issn.1674-7445.2020.04.015
引用本文: 庄锦炀, 刘东, 邓庚国, 等. Klotho:一个潜在的移植肾保护蛋白[J]. 器官移植, 2020, 11(4): 508-515. doi: 10.3969/j.issn.1674-7445.2020.04.015
Zhuang Jinyang, Liu Dong, Deng Gengguo, et al. Klotho: a potential protective protein for renal graft[J]. ORGAN TRANSPLANTATION, 2020, 11(4): 508-515. doi: 10.3969/j.issn.1674-7445.2020.04.015
Citation: Zhuang Jinyang, Liu Dong, Deng Gengguo, et al. Klotho: a potential protective protein for renal graft[J]. ORGAN TRANSPLANTATION, 2020, 11(4): 508-515. doi: 10.3969/j.issn.1674-7445.2020.04.015

Klotho:一个潜在的移植肾保护蛋白

doi: 10.3969/j.issn.1674-7445.2020.04.015
基金项目: 

广东省医学科研基金 A2020371

详细信息
    作者简介:

    庄锦炀,男,硕士研究生,研究方向为泌尿外科,Email:624996573@qq.com

    通讯作者:

    刘东,男,博士,主任医师,研究方向为泌尿外科及器官移植,Email:ld177@163.com

  • 中图分类号: R617, R341

Klotho: a potential protective protein for renal graft

More Information
  • 摘要: Klotho基因是高表达于肾脏的一种抗衰老基因,其编码产物Klotho蛋白对肾脏组织的炎症反应、氧化应激损伤及细胞凋亡等具有抑制作用,是一种肾脏保护蛋白,有望成为新的肾脏疾病治疗靶点。本文就Klotho的生物学特点以及Klotho对移植肾功能的保护作用进行综述。

     

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出版历程
  • 收稿日期:  2020-04-24
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2020-07-15

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