中国肾脏移植受者消化系统并发症临床诊疗指南

中华医学会器官移植学分会; 杨猛; 秦文瀚; 王卫黎; 李有赞; 赵洪雯

doi:10.3969/j.issn.1674-7445.2024126

中国肾脏移植受者消化系统并发症临床诊疗指南

doi: 10.3969/j.issn.1674-7445.2024126

400038　重庆，陆军军医大学第一附属医院

基金项目: 全军临床重点专科建设（41561Z23785）

详细信息

通讯作者:
赵洪雯，Email：zhaohongwen@tmmu.edu.cn

中图分类号: R617, R57
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- 被引次数: 0
出版历程
- 收稿日期: 2024-04-18
- 网络出版日期: 2024-05-16
- 刊出日期: 2024-07-15

Clinical diagnosis and treatment guidelines for digestive system complications in kidney transplant recipients in China

Branch of Organ Transplantation of Chinese Medical Association,

The First Affiliated Hospital of the Army Medical University, Chongqing 400038, China

More Information

Corresponding author: Zhao Hongwen, Email: zhaohongwen@tmmu.edu.cn

摘要

摘要: 肾脏移植受者消化系统并发症的诊治关系患者长期存活及生存质量，需要高度关注，为进一步规范其诊断与治疗，中华医学会器官移植学分会发起制订《中国肾脏移植受者消化系统并发症临床诊疗指南》，并组织器官移植学和相关学科专家，依据现有临床研究、系统评价、病例研究、专家共识和指南等，总结近年来国内外在肾脏移植受者消化系统并发症诊治方面的新进展，经过多次研讨达成一致意见后撰写成文。全文围绕11个临床问题，形成16条推荐意见，使用2009版牛津大学循证医学中心的证据分级与推荐强度标准对每个临床问题的证据质量和推荐强度进行分级，以期为肾脏移植受者消化系统并发症的诊疗提供参考，全面提升临床医师对消化系统并发症的管理能力，造福移植受者。
- 肾脏移植 /
- 消化系统并发症 /
- 腹泻 /
- 消化道出血 /
- 急性胰腺炎 /
- 炎症性肠病 /
- 肠道菌群失衡 /
- 免疫抑制药
Abstract: The diagnosis and treatment of digestive system complications of kidney transplant recipients is related to the long-term survival and quality of life of patients, which needs great attention. In order to further standardize its diagnosis and treatment, Branch of Organ Transplantation of Chinese Medical Association initiated the formulation of “Clinical Diagnosis and Treatment Guidelines for Digestive System Complications in Kidney Transplant Recipients in China”, and organized experts in organ transplantation and related disciplines to summarize the new progress in diagnosis and treatment of digestive system complications of kidney transplant recipients at home and abroad in recent years based on existing clinical research, systematic evaluation, case study, expert consensus and existing guidelines, and reached a consensus after many discussions. This paper focuses on 11 clinical problems, forming 16 recommendations, and grading the evidence quality and recommendation strength of each clinical problem by the evidence grading and recommendation strength standard of Oxford University Evidence-based Medicine Center in 2009, in order to provide reference for the diagnosis and treatment of digestive system complications of kidney transplant recipients, comprehensively improve the management ability of digestive system complications of clinicians in an all-round way and benefit transplant recipients.
- Kidney transplantation /
- Digestive system complication /
- Diarrhea /
- Gastrointestinal bleeding /
- Acute pancreatitis /
- Inflammatory bowel disease /
- Imbalance of gut microbiota /
- Immunosuppressant

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FIG. 3247. FIG. 3247.

FIG. 3247.. FIG. 3247.

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表 1 2009版OCEBM证据分级与推荐意见强度分级标准

Table 1. Level of evidence and recommended strength grades of OCEBM in 2009

推荐强度	证据等级	描述
A	1a	多项随机对照试验的系统评价
	1b	结果可信区间小的随机对照试验
	1c	显示“全或无效应”的任何证据
B	2a	队列研究的系统评价
	2b	单个的队列研究（包括低质量的随机对照试验，如失访率>20%者）
	2c	基于患者结局的研究
	3a	病例对照研究的系统评价
	3b	单个病例对照研究
C	4	病例系列报告、低质量队列研究和低质量病例对照研究
D	5	专家意见（即无临床研究支持仅依据基础研究或临床经验的推测）

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