王浩钧, 孙泽家, 王玮. 移植肾纤维化的诊断和治疗优化方案[J]. 器官移植, 2024, 15(1): 19-25. DOI: 10.3969/j.issn.1674-7445.2023156
引用本文: 王浩钧, 孙泽家, 王玮. 移植肾纤维化的诊断和治疗优化方案[J]. 器官移植, 2024, 15(1): 19-25. DOI: 10.3969/j.issn.1674-7445.2023156
Wang Haojun, Sun Zejia, Wang Wei. Optimal diagnosis and treatment for renal allograft fibrosis[J]. ORGAN TRANSPLANTATION, 2024, 15(1): 19-25. DOI: 10.3969/j.issn.1674-7445.2023156
Citation: Wang Haojun, Sun Zejia, Wang Wei. Optimal diagnosis and treatment for renal allograft fibrosis[J]. ORGAN TRANSPLANTATION, 2024, 15(1): 19-25. DOI: 10.3969/j.issn.1674-7445.2023156

移植肾纤维化的诊断和治疗优化方案

Optimal diagnosis and treatment for renal allograft fibrosis

  • 摘要: 移植肾纤维化是肾移植术后常见且严重的并发症之一,严重影响移植肾的功能和存活率,甚至可能导致器官衰竭和患者死亡。目前关于移植肾纤维化的研究非常复杂,包括免疫、缺血-再灌注损伤、感染、药物毒性等,移植肾纤维化的诊断和治疗依然极具挑战性。本文旨在总结当前研究的最新进展,深入探讨移植肾纤维化的成因以及最新的诊断和治疗方法。通过提高诊断的准确率和优化治疗方案,有望改善肾移植受者的预后,也将为临床医师更好地管理肾移植受者提供参考。

     

    Abstract: Renal allograft fibrosis is one of the common and severe complications after kidney transplantation, which seriously affects the function and survival rate of renal allograft, and may even lead to organ failure and patient death. At present, the researches on renal allograft fibrosis are highly complicated, including immunity, ischemia-reperfusion injury, infection and drug toxicity, etc. The diagnosis and treatment of renal allograft fibrosis remain extremely challenging. In this article, the latest research progress was reviewed and the causes, novel diagnosis and treatment strategies for renal allograft fibrosis were investigated. By improving diagnostic accuracy and optimizing treatment regimen, it is expected to enhance clinical prognosis of kidney transplant recipients, aiming to provide reference for clinicians to deliver proper management for kidney transplant recipients.

     

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