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肾移植围手术期康复治疗研究进展

马晓杰, 姚波暖, 游咏, 等. 肾移植围手术期康复治疗研究进展[J]. 器官移植, 2023, 14(3): 466-472. doi: 10.3969/j.issn.1674-7445.2023.03.021
引用本文: 马晓杰, 姚波暖, 游咏, 等. 肾移植围手术期康复治疗研究进展[J]. 器官移植, 2023, 14(3): 466-472. doi: 10.3969/j.issn.1674-7445.2023.03.021
Ma Xiaojie, Yao Bonuan, You Yong, et al. Research progress on perioperative rehabilitation of kidney transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(3): 466-472. doi: 10.3969/j.issn.1674-7445.2023.03.021
Citation: Ma Xiaojie, Yao Bonuan, You Yong, et al. Research progress on perioperative rehabilitation of kidney transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(3): 466-472. doi: 10.3969/j.issn.1674-7445.2023.03.021

肾移植围手术期康复治疗研究进展

doi: 10.3969/j.issn.1674-7445.2023.03.021
基金项目: 

海南省自然科学基金 821QN409

海南省自然科学基金高层次人才项目 820RC766

海南省卫生健康行业科研项目 20A200360

详细信息
    作者简介:
    通讯作者:

    蒋鸿涛(ORCID:0000-0001-9716-3233),主任医师,医学硕士,硕士研究生导师,研究方向为肾移植,Email: jht20032003@163.com

  • 中图分类号: R617, R493

Research progress on perioperative rehabilitation of kidney transplantation

More Information
  • 摘要: 肾移植是临床治疗终末期肾病最有效的手段,与接受透析治疗的患者相比,肾移植受者的生存率和生活质量较高,临床结局更好。但肾移植受者常存在衰弱、心肺功能下降、认知功能障碍等生理功能障碍及心理功能障碍。近年来,随着加速康复外科概念的应用,康复治疗在优化术前基线功能、减少围手术期生理及心理应激反应、降低术后并发症发生率等方面发挥着举足轻重的作用。本文就加速康复外科在肾移植中的应用进行综述,总结肾移植预康复、术后急性期康复治疗的研究进展,为肾移植围手术期康复治疗提供参考,以期改善肾移植受者的生存质量及促进肾移植技术的发展。

     

  • [1] ZHANG L, WANG F, WANG L, et al. Prevalence of chronic kidney disease in China: a cross-sectional survey[J]. Lancet, 2012, 379(9818): 815-822. DOI: 10.1016/S0140-6736(12)60033-6.
    [2] HAKAMÄKI M, JÄRVISALO MJ, LANKINEN R, et al. Evolution of quality of life in chronic kidney disease stage 4-5 patients transitioning to dialysis and transplantation[J]. Nephron, 2022, 146(5): 439-448. DOI: 10.1159/000521771.
    [3] WILKINSON TJ, MIKSZA J, ZACCARDI F, et al. Associations between frailty trajectories and cardiovascular, renal, and mortality outcomes in chronic kidney disease[J]. J Cachexia Sarcopenia Muscle, 2022, 13(5): 2426-2435. DOI: 10.1002/jcsm.13047.
    [4] 国家卫生健康委员会医管中心加速康复外科专家委员会器官移植学组. 中国肾移植围手术期加速康复管理专家共识(2018版)[J/CD]. 中华移植杂志(电子版), 2018, 12(4): 151-156. DOI: 10.3877/cma.j.issn.1674-3903.2018.04.002.

    Organ Transplantation Group, Expert Committee of Accelerated Rehabilitation Surgery of National Health Commission. Expert consensus on the management of perioperative accelerated rehabilitation of kidney transplantation in China (2018 edition)[J/CD]. Chin J Transplant (Electr Edit), 2018, 12(4): 151-156. DOI: 10.3877/cma.j.issn.1674-3903.2018.04.002.
    [5] TAN JHS, BHATIA K, SHARMA V, et al. Enhanced recovery after surgery recommendations for renal transplantation: guidelines[J]. Br J Surg, 2022, 110(1): 57-59. DOI: 10.1093/bjs/znac325.
    [6] PRIONAS A, CRADDOCK C, PAPALOIS V. Enhanced recovery after renal transplantation decreases recipients' urological complications and hospital stay: a systematic review and meta-analysis[J]. J Clin Med, 2021, 10(11): 2286. DOI: 10.3390/jcm10112286.
    [7] DIAS BH, RANA AAM, OLAKKENGIL SA, et al. Development and implementation of an enhanced recovery after surgery protocol for renal transplantation[J]. ANZ J Surg, 2019, 89(10): 1319-1323. DOI: 10.1111/ans.15461.
    [8] ELSABBAGH AM, GHONEIM I, MOIZ A, et al. Enhanced recovery after surgery pathway in kidney transplantation: the road less traveled[J]. Transplant Direct, 2022, 8(7): e1333. DOI: 10.1097/TXD.0000000000001333.
    [9] CABILAN CJ, HINES S, MUNDAY J. The effectiveness of prehabilitation or preoperative exercise for surgical patients: a systematic review[J]. JBI Database System Rev Implement Rep, 2015, 13(1): 146-187. DOI: 10.11124/jbisrir-2015-1885.
    [10] MOLENAAR CJ, VAN ROOIJEN SJ, FOKKENROOD HJ, et al. Prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery[J]. Cochrane Database Syst Rev, 2022, 5(5): CD013259. DOI: 10.1002/14651858.CD013259.pub2.
    [11] 商娜, 郭树彬. 衰弱评估——老年急诊领域的机遇和挑战[J]. 中国急救医学, 2022, 42(6): 541-544. DOI: 10.3969/j.issn.1002-1949.2022.06.015.

    SHANG N, GUO SB. Frailty assessment: opportunities and challenges in the field of geriatric emergency medicine[J]. Chin J Crit Care Med, 2022, 42(6): 541-544. DOI: 10.3969/j.issn.1002-1949.2022.06.015.
    [12] SANTOS DGMD, PALLONE JM, MANZINI CSS, et al. Relationship between frailty, social support and family functionality of hemodialysis patients: a cross-sectional study[J]. Sao Paulo Med J, 2021, 139(6): 570-575. DOI: 10.1590/1516-3180.2021.0089.R1.0904221.
    [13] HAUGEN CE, CHU NM, YING H, et al. Frailty and access to kidney transplantation[J]. Clin J Am Soc Nephrol, 2019, 14(4): 576-582. DOI: 10.2215/CJN.12921118.
    [14] SCHAENMAN J, CASTELLON L, LIANG EC, et al. The frailty risk score predicts length of stay and need for rehospitalization after kidney transplantation in a retrospective cohort: a pilot study[J]. Pilot Feasibility Stud, 2019, 5: 144. DOI: 10.1186/s40814-019-0534-2.
    [15] KAO J, REID N, HUBBARD RE, et al. Frailty and solid-organ transplant candidates: a scoping review[J]. BMC Geriatr, 2022, 22(1): 864. DOI: 10.1186/s12877-022-03485-7.
    [16] PÉREZ-SÁEZ MJ, ARIAS-CABRALES CE, REDONDO-PACHÓN D, et al. Increased mortality after kidney transplantation in mildly frail recipients[J]. Clin Kidney J, 2022, 15(11): 2089-2096. DOI: 10.1093/ckj/sfac159.
    [17] MA X, ZHANG Z, PENG M, et al. Face-to-face mentoring, remotely supervised home exercise prehabilitation to improve physical function in patients awaiting kidney transplantation: a randomized clinical trial[J]. Front Psychol, 2022, 13: 831445. DOI: 10.3389/fpsyg.2022.831445.
    [18] UCHIYAMA K, ADACHI K, MURAOKA K, et al. Home-based aerobic exercise and resistance training for severe chronic kidney disease: a randomized controlled trial[J]. J Cachexia Sarcopenia Muscle, 2021, 12(6): 1789-1802. DOI: 10.1002/jcsm.12775.
    [19] MATSUSHITA K, BALLEW SH, WANG AY, et al. Epidemiology and risk of cardiovascular disease in populations with chronic kidney disease[J]. Nat Rev Nephrol, 2022, 18(11): 696-707. DOI: 10.1038/s41581-022-00616-6.
    [20] LIM K, TING SMS, HAMBORG T, et al. Cardiovascular functional reserve before and after kidney transplant[J]. JAMA Cardiol, 2020, 5(4): 420-429. DOI: 10.1001/jamacardio.2019.5738.
    [21] LAW JP, PICKUP L, PAVLOVIC D, et al. Hypertension and cardiomyopathy associated with chronic kidney disease: epidemiology, pathogenesis and treatment considerations[J]. J Hum Hypertens, 2023, 37(1): 1-19. DOI: 10.1038/s41371-022-00751-4.
    [22] CLARKSON MJ, BENNETT PN, FRASER SF, et al. Exercise interventions for improving objective physical function in patients with end-stage kidney disease on dialysis: a systematic review and meta-analysis[J]. Am J Physiol Renal Physiol, 2019, 316(5): F856-F872. DOI: 10.1152/ajprenal.00317.2018.
    [23] YAMAMOTO R, ITO T, NAGASAWA Y, et al. Efficacy of aerobic exercise on the cardiometabolic and renal outcomes in patients with chronic kidney disease: a systematic review of randomized controlled trials[J]. J Nephrol, 2021, 34(1): 155-164. DOI: 10.1007/s40620-020-00865-3.
    [24] EXEL AL, LIMA PS, URTADO CB, et al. Effectiveness of a resistance exercise program for lower limbs in chronic renal patients on hemodialysis: a randomized controlled trial[J]. Hemodial Int, 2021, DOI: 10.1111/hdi.12918[Epubaheadofprint].
    [25] YABE H, KONO K, YAMAGUCHI T, et al. Effects of intradialytic exercise for advanced-age patients undergoing hemodialysis: a randomized controlled trial[J]. PLoS One, 2021, 16(10): e0257918. DOI: 10.1371/journal.pone.0257918.
    [26] HIDAKA S, NISHIMIURA A, HIRATA M, et al. Prevalence of mild cognitive impairment and its association with handgrip strength in patients on hemodialysis[J]. Sci Rep, 2022, 12(1): 3850. DOI: 10.1038/s41598-022-07550-4.
    [27] YUAN H, LI H, MU J, et al. Reduced cortical complexity in patients with end-stage kidney disease prior to dialysis initiation[J]. Front Neurosci, 2022, 16: 971010. DOI: 10.3389/fnins.2022.971010.
    [28] MIRANDA AS, CORDEIRO TM, DOS SANTOS LACERDA SOARES TM, et al. Kidney-brain axis inflammatory cross-talk: from bench to bedside[J]. Clin Sci (Lond), 2017, 131(11): 1093-1105. DOI: 10.1042/CS20160927.
    [29] CHU NM, MCADAMS-DEMARCO MA. Exercise and cognitive function in patients with end-stage kidney disease[J]. Semin Dial, 2019, 32(4): 283-290. DOI: 10.1111/sdi.12804.
    [30] BAGGETTA R, D'ARRIGO G, TORINO C, et al. Effect of a home based, low intensity, physical exercise program in older adults dialysis patients: a secondary analysis of the EXCITE trial[J]. BMC Geriatr, 2018, 18(1): 248. DOI: 10.1186/s12877-018-0938-5.
    [31] BOGATAJ Š, MESARIČ KK, PAJEK M, et al. Physical exercise and cognitive training interventions to improve cognition in hemodialysis patients: a systematic review[J]. Front Public Health, 2022, 10: 1032076. DOI: 10.3389/fpubh.2022.1032076.
    [32] MCADAMS-DEMARCO MA, KONEL J, WARSAME F, et al. Intradialytic cognitive and exercise training may preserve cognitive function[J]. Kidney Int Rep, 2017, 3(1): 81-88. DOI: 10.1016/j.ekir.2017.08.006.
    [33] PELLEGRINI-LAPLAGNE M, DUPUY O, SOSNER P, et al. Acute effect of a simultaneous exercise and cognitive task on executive functions and prefrontal cortex oxygenation in healthy older adults[J]. Brain Sci, 2022, 12(4): 455. DOI: 10.3390/brainsci12040455.
    [34] ANWAR W, EZZAT H, MOHAB A. Comparative study of impact of hemodialysis and renal transplantation on cognitive functions in ESRD patients[J]. Nefrologia, 2015, 35(6): 567-571. DOI: 10.1016/j.nefro.2015.07.004.
    [35] CHEN X, CHU NM, BASYAL PS, et al. Depressive symptoms at kidney transplant evaluation and access to the kidney transplant waitlist[J]. Kidney Int Rep, 2022, 7(6): 1306-1317. DOI: 10.1016/j.ekir.2022.03.008.
    [36] CHO S, PARK S, KIM JE, et al. Incidence of depression in kidney transplant recipients in South Korea: a long-term population-based study[J]. Sci Rep, 2022, 12(1): 17603. DOI: 10.1038/s41598-022-20828-x.
    [37] LAI YL, NEO HLM, VATHSALA A, et al. Comparing emotional adjustment of living-donor and deceased-donor kidney transplant patients[J]. Transplant Direct, 2020, 6(2): e529. DOI: 10.1097/TXD.0000000000000956.
    [38] CAYLEY WE JR. Exercise training for adults undergoing maintenance dialysis[J]. Am Fam Physician, 2022, 106(2): 135-136.
    [39] ALHAWATMEH H, ALSHAMMARI S, RABABAH JA. Effects of mindfulness meditation on trait mindfulness, perceived stress, emotion regulation, and quality of life in hemodialysis patients: a randomized controlled trial[J]. Int J Nurs Sci, 2022, 9(2): 139-146. DOI: 10.1016/j.ijnss.2022.03.004.
    [40] VAISHNAV BS, HIRAPARA JJ, SHAH MK. Study of effect of guided meditation on quality of life in patients of end stage renal disease (ESRD) on maintenance hemodialysis - a randomised controlled trial[J]. BMC Complement Med Ther, 2022, 22(1): 238. DOI: 10.1186/s12906-022-03717-8.
    [41] PIO TMT, PRIHANTO JB, JAHAN Y, et al. Assessing burden, anxiety, depression, and quality of life among caregivers of hemodialysis patients in indonesia: a cross-sectional study[J]. Int J Environ Res Public Health, 2022, 19(8): 4544. DOI: 10.3390/ijerph19084544.
    [42] PÉREZ-SÁEZ MJ, MORGADO-PÉREZ A, FAURA A, et al. The FRAILMar study protocol: frailty in patients with advanced chronic kidney disease awaiting kidney transplantation. a randomized clinical trial of multimodal prehabilitation[J]. Front Med (Lausanne), 2021, 8: 675049. DOI: 10.3389/fmed.2021.675049.
    [43] MA X, ZHANG Z, YAO B, et al. Study on the effect of pre-rehabilitation home-based on patients undergoing kidney transplantation with end-stage renal disease: a study protocol[J]. Medicine (Baltimore), 2021, 100(52): e28280. DOI: 10.1097/MD.0000000000028280.
    [44] 中华医学会外科学分会, 中华医学会麻醉学分会. 加速康复外科中国专家共识及路径管理指南(2018版)[J]. 中国实用外科杂志, 2018, 38(1): 1-20. DOI: 10.19538/j.cjps.issn1005-2208.2018.01.01.

    Surgery Branch of Chinese Medical Association, Anesthesiology Branch of Chinese Medical Association. Chinese expert consensus and pathway management guidelines for accelerated rehabilitation surgery(2018 edition)[J]. Chin J Pract Surg, 2018, 38(1): 1-20. DOI: 10.19538/j.cjps.issn1005-2208.2018.01.01.
    [45] GRASS F, PACHE B, MARTIN D, et al. Feasibility of early postoperative mobilisation after colorectal surgery: a retrospective cohort study[J]. Int J Surg, 2018, 56: 161-166. DOI: 10.1016/j.ijsu.2018.06.024.
    [46] SCHALLER SJ, ANSTEY M, BLOBNER M, et al. Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial[J]. Lancet, 2016, 388(10052): 1377-1388. DOI: 10.1016/S0140-6736(16)31637-3.
    [47] CAMPANATI-PALHARES L, SIMONCINI TC, DA SILVA AUGUSTO PG, et al. Effects of a physiotherapeutic protocol in respiratory function, aerobic capacity and quality of life after kidney transplantation[J]. Transplant Proc, 2018, 50(3): 750-753. DOI: 10.1016/j.transproceed.2018.02.045.
    [48] CASSIDY MR, ROSENKRANZ P, MACHT RD, et al. The I COUGH multidisciplinary perioperative pulmonary care program: one decade of experience[J]. Jt Comm J Qual Patient Saf, 2020, 46(5): 241-249. DOI: 10.1016/j.jcjq.2020.01.005.
    [49] BANG SM, JANG MJ, KIM KH, et al. Prevention of venous thromboembolism, 2nd edition: Korean Society of Thrombosis and Hemostasis evidence-based clinical practice guidelines[J]. J Korean Med Sci, 2014, 29(2): 164-171. DOI: 10.3346/jkms.2014.29.2.164.
    [50] JUN KW, PARK KM, KIM MH, et al. Mechanical thromboprophylaxis is sufficient to prevent the lower extremity deep vein thrombosis after kidney transplantation[J]. Ann Surg Treat Res, 2014, 87(1): 28-34. DOI: 10.4174/astr.2014.87.1.28.
    [51] KIM MH, JUN KW, HWANG JK, et al. Incidence and outcome of isolated distal deep vein thrombosis in kidney transplant recipients[J]. Ann Surg Treat Res, 2020, 98(6): 324-331. DOI: 10.4174/astr.2020.98.6.324.
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  • 收稿日期:  2023-01-04
  • 刊出日期:  2023-05-15

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