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巨噬细胞在移植后慢性排斥反应中的作用研究进展

任滌非, 廖涛, 苗芸. 巨噬细胞在移植后慢性排斥反应中的作用研究进展[J]. 器官移植, 2023, 14(3): 358-363. doi: 10.3969/j.issn.1674-7445.2023.03.006
引用本文: 任滌非, 廖涛, 苗芸. 巨噬细胞在移植后慢性排斥反应中的作用研究进展[J]. 器官移植, 2023, 14(3): 358-363. doi: 10.3969/j.issn.1674-7445.2023.03.006
Ren Difei, Liao Tao, Miao Yun. Research progress on the role of macrophages in post-transplantation chronic rejection[J]. ORGAN TRANSPLANTATION, 2023, 14(3): 358-363. doi: 10.3969/j.issn.1674-7445.2023.03.006
Citation: Ren Difei, Liao Tao, Miao Yun. Research progress on the role of macrophages in post-transplantation chronic rejection[J]. ORGAN TRANSPLANTATION, 2023, 14(3): 358-363. doi: 10.3969/j.issn.1674-7445.2023.03.006

巨噬细胞在移植后慢性排斥反应中的作用研究进展

doi: 10.3969/j.issn.1674-7445.2023.03.006
基金项目: 

国家自然科学基金 82270784

国家自然科学基金 82070770

国家自然科学基金 82170767

大学生创新创业训练计划项目 202212121242

详细信息
    作者简介:
    通讯作者:

    苗芸(ORCID:0000-0003-3592-4695),博士,主任医师,研究方向为肾移植,Email:miaoyunecho@126.com

  • 中图分类号: R617, R329.2

Research progress on the role of macrophages in post-transplantation chronic rejection

More Information
  • 摘要: 器官移植是治疗终末期器官病变的最佳方法,然而排斥反应仍然是影响移植物存活的重要因素。目前,针对急性排斥反应的治疗方法效果良好,但对慢性排斥反应仍缺乏有效的治疗手段,长期慢性排斥反应可能导致移植物失功,严重影响移植物的长期存活率。近年来,巨噬细胞在慢性排斥反应中的作用逐渐受到关注。本文对慢性排斥反应的主要病理变化、参与慢性排斥反应巨噬细胞的多样性及功能差异、巨噬细胞参与慢性排斥反应的作用及机制进行综述,并总结巨噬细胞相关慢性排斥反应治疗的研究进展,以期为巨噬细胞在器官移植术后慢性排斥反应中的作用研究提供参考。

     

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  • 收稿日期:  2022-12-04
  • 刊出日期:  2023-05-15

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