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人体子宫移植相关要点讨论

刘宇, 丁岩, 张旭垠, 等. 人体子宫移植相关要点讨论[J]. 器官移植, 2023, 14(2): 305-312. doi: 10.3969/j.issn.1674-7445.2023.02.019
引用本文: 刘宇, 丁岩, 张旭垠, 等. 人体子宫移植相关要点讨论[J]. 器官移植, 2023, 14(2): 305-312. doi: 10.3969/j.issn.1674-7445.2023.02.019
Liu Yu, Ding Yan, Zhang Xuyin, et al. Highlights of human uterus transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(2): 305-312. doi: 10.3969/j.issn.1674-7445.2023.02.019
Citation: Liu Yu, Ding Yan, Zhang Xuyin, et al. Highlights of human uterus transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(2): 305-312. doi: 10.3969/j.issn.1674-7445.2023.02.019

人体子宫移植相关要点讨论

doi: 10.3969/j.issn.1674-7445.2023.02.019
基金项目: 

国家重点研发计划 VEG157011

国家自然科学基金青年科学基金 8190061150

详细信息
    作者简介:
    通讯作者:

    华克勤,博士,教授,主任医师,研究方向为生殖内分泌、妇科肿瘤及妇科微创医学,E-mail: huakeqin@126.com

  • 中图分类号: R617, R711.74

Highlights of human uterus transplantation

More Information
  • 摘要: 子宫移植作为一种新兴的实体器官移植,已成为子宫性不孕女性获取生物学后代的重要方式。子宫移植手术本身存在血管蒂提取、器官灌注及血管缝合等方面的技术挑战,但随着子宫移植动物造模及尸体移植手术的开展及应用,子宫移植供受者的选择、子宫血管的选择、子宫移植的并发症及其防治、移植物活力评估、妊娠及分娩时机的选择、子宫切除时机的选择及供受者心理健康及后代健康等问题越发成为讨论的新热点。本文根据全球现有人体子宫移植数据及结局,就以上热点问题进行综述,以期为促进国内人体子宫移植研究的开展和取得更长远的进步提供参考。

     

  • 表  1  目前子宫移植的免疫抑制方案

    Table  1.   Current immunosuppressive regimen for uterine transplantation

    药物 时间(d)
    0 1 2 3 4 5 6 7 ≥8
    甲泼尼龙(静脉滴注,500 mg)  
    抗胸腺细胞球蛋白(静脉滴注,5 mg/kg,每日2次)          
    他克莫司[口服,0.1 mg/(kg·d),每日2次]            
    吗替麦考酚酯(口服,1 g,每日2次)
    泼尼松(口服,5 mg,每日1次)  
    下载: 导出CSV
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出版历程
  • 收稿日期:  2022-10-19
  • 网络出版日期:  2023-03-15
  • 刊出日期:  2023-03-15

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