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管周毛细血管损伤在肾移植中作用的研究进展

梁诚, 牛纪平, 满江位, 等. 管周毛细血管损伤在肾移植中作用的研究进展[J]. 器官移植, 2023, 14(1): 147-153. doi: 10.3969/j.issn.1674-7445.2023.01.020
引用本文: 梁诚, 牛纪平, 满江位, 等. 管周毛细血管损伤在肾移植中作用的研究进展[J]. 器官移植, 2023, 14(1): 147-153. doi: 10.3969/j.issn.1674-7445.2023.01.020
Liang Cheng, Niu Jiping, Man Jiangwei, et al. Progress in the role of peritubular capillary injury in kidney transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(1): 147-153. doi: 10.3969/j.issn.1674-7445.2023.01.020
Citation: Liang Cheng, Niu Jiping, Man Jiangwei, et al. Progress in the role of peritubular capillary injury in kidney transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(1): 147-153. doi: 10.3969/j.issn.1674-7445.2023.01.020

管周毛细血管损伤在肾移植中作用的研究进展

doi: 10.3969/j.issn.1674-7445.2023.01.020
基金项目: 

甘肃省青年科技基金 21JR7RA428

兰州大学第二医院“萃英科技创新”计划项目 CY2021-QN-B15

详细信息
    作者简介:
    通讯作者:

    杨立,博士,主任医师,研究方向为肾移植与再灌注损伤,Email: ery_yangli@lzu.edu.cn

  • 中图分类号: R617, R322.6+1

Progress in the role of peritubular capillary injury in kidney transplantation

More Information
  • 摘要: 肾脏是一个高度血管化的器官,管周毛细血管网络是其微血管系统中关键组成部分。管周毛细血管作为肾小管及肾间质的主要供应血管,参与肾小管的能量代谢、物质分泌和重吸收等重要生理过程。近年来研究发现,肾移植过程中的缺血-再灌注损伤、排斥反应以及肾脏纤维化过程均会引起管周毛细血管结构完整性破坏、数量减少,并加重移植肾间质纤维化,严重影响肾功能的长期稳定。因此,本文对管周毛细血管的结构与功能,管周毛细血管与缺血-再灌注损伤、排斥反应以及移植肾纤维化进行综述,聚焦肾移植期间管周毛细血管的损伤机制和特异性改变,为防治肾移植围手术期并发症,改善移植物的长期预后提供参考。

     

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出版历程
  • 收稿日期:  2022-08-01
  • 网络出版日期:  2023-01-17
  • 刊出日期:  2023-01-15

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