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脑卒中供者心脏的心肌损伤机制与临床研究进展

王小文, 郑哲, 黄洁. 脑卒中供者心脏的心肌损伤机制与临床研究进展[J]. 器官移植, 2023, 14(1): 42-48. doi: 10.3969/j.issn.1674-7445.2023.01.005
引用本文: 王小文, 郑哲, 黄洁. 脑卒中供者心脏的心肌损伤机制与临床研究进展[J]. 器官移植, 2023, 14(1): 42-48. doi: 10.3969/j.issn.1674-7445.2023.01.005
Wang Xiaowen, Zheng Zhe, Huang Jie. Clinical research progress and mechanism on myocardial injury in hearts from donors with stroke[J]. ORGAN TRANSPLANTATION, 2023, 14(1): 42-48. doi: 10.3969/j.issn.1674-7445.2023.01.005
Citation: Wang Xiaowen, Zheng Zhe, Huang Jie. Clinical research progress and mechanism on myocardial injury in hearts from donors with stroke[J]. ORGAN TRANSPLANTATION, 2023, 14(1): 42-48. doi: 10.3969/j.issn.1674-7445.2023.01.005

脑卒中供者心脏的心肌损伤机制与临床研究进展

doi: 10.3969/j.issn.1674-7445.2023.01.005
基金项目: 

国家重点研发计划项目 2016YFC1300900

创新工程-中国医学科学院临床与转化医学研究专项 2022-I2M-C & T-B-038

详细信息
    作者简介:
    通讯作者:

    郑哲,Email:zhengzhe@fuwai.com

    黄洁,Email:huangjie@fuwai.com

  • 中图分类号: R617, R722.15+1, R541

Clinical research progress and mechanism on myocardial injury in hearts from donors with stroke

More Information
  • 摘要: 脑死亡供者心脏是目前心脏移植最主要的器官来源。脑死亡发生后会出现严重的血流动力学改变和一系列器官功能变化,进而造成组织器官的功能损害甚至丧失,尤其是心脏。神经系统和心血管系统的生理、病理生理之间存在密切联系和相互作用,脑卒中发生后,通过脑-心轴反应导致自主神经失调、神经内分泌紊乱和强烈而持续的炎症反应,引发交感风暴、儿茶酚胺风暴、炎症风暴等导致脑卒中所致心脏损伤。本文旨在对近年来有关脑卒中供者心脏心肌损伤的机制研究及其对心脏移植术后疗效和预后影响的相关研究进行综述,为临床实践和进一步研究提供参考。

     

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出版历程
  • 收稿日期:  2022-11-03
  • 网络出版日期:  2023-01-17
  • 刊出日期:  2023-01-15

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