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胆道闭锁的外科诊治进展

李晓斌, 傅斌生. 胆道闭锁的外科诊治进展[J]. 器官移植, 2022, 13(6): 818-824. doi: 10.3969/j.issn.1674-7445.2022.06.019
引用本文: 李晓斌, 傅斌生. 胆道闭锁的外科诊治进展[J]. 器官移植, 2022, 13(6): 818-824. doi: 10.3969/j.issn.1674-7445.2022.06.019
Li Xiaobin, Fu Binsheng. Research progress on diagnosis and surgical treatment of biliary atresia[J]. ORGAN TRANSPLANTATION, 2022, 13(6): 818-824. doi: 10.3969/j.issn.1674-7445.2022.06.019
Citation: Li Xiaobin, Fu Binsheng. Research progress on diagnosis and surgical treatment of biliary atresia[J]. ORGAN TRANSPLANTATION, 2022, 13(6): 818-824. doi: 10.3969/j.issn.1674-7445.2022.06.019

胆道闭锁的外科诊治进展

doi: 10.3969/j.issn.1674-7445.2022.06.019
基金项目: 

国家自然科学基金面上项目 2020GZRPYMS04

广东省基础与应用基础研究基金 2020A1515010302

详细信息
    作者简介:
    通讯作者:

    傅斌生,博士,主任医师,研究方向为肝移植,Email:fubinsh@mail.sysu.edu.cn

  • 中图分类号: R617, R657.4+4

Research progress on diagnosis and surgical treatment of biliary atresia

More Information
  • 摘要: 胆道闭锁是一种病因不明、以胆道梗阻为特点的儿童先天性罕见疾病,主要表现为肝内外胆道系统的进行性炎症以及纤维性梗阻,进而发展为胆汁淤积性肝硬化、肝衰竭。胆道闭锁虽然罕见,但它是婴幼儿胆汁淤积性疾病的最常见原因,如不经手术治疗(如Kasai手术、肝移植手术),患儿通常可在短期内死亡。Kasai手术可改善胆道引流,但不能改变胆道闭锁患儿的结局,大多数仍会因为胆汁淤积而遭受持续的肝损伤,最终需要进行肝移植。而目前关于肝移植术前是否行Kasai手术尚未达成一致意见。本文就胆道闭锁的诊断、外科治疗现状等进行综述,以期为临床胆道闭锁的诊断和治疗提供参考,改善胆道闭锁患儿的生存。

     

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出版历程
  • 收稿日期:  2022-07-10
  • 网络出版日期:  2022-11-14
  • 刊出日期:  2022-11-15

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