Application and research progress on mesenchymal stem cell in organ transplantation
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摘要: 器官移植是终末期器官功能衰竭的有效治疗方法。然而, 移植受体需长期使用免疫抑制剂以降低器官移植免疫排斥反应。间充质干细胞(MSC)具有独特的免疫学特性, 有望在器官移植中发挥重要作用。本文总结了MSC的免疫学特性, 并就其在器官移植中减轻免疫排斥反应、诱导免疫耐受、促进组织修复、诱导新生血管形成以及在异种器官移植中的作用等方面的研究进展进行了简述, 以期为MSC应用于器官移植提供参考。
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