Research progress on lung transplantation after allogeneic hematopoietic stem cell transplantation
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摘要: 迟发型非感染性肺部并发症(LONIPC)是异基因造血干细胞移植(HSCT)术后慢性移植物抗宿主病(cGVHD)的重要部分, 目前缺乏有效的药物治疗方法。虽然肺移植是治疗多数终末期肺病的唯一方法, 但由于HSCT术后受体潜在的风险, 肺移植难以广泛应用。本文结合世界各地多个移植中心针对HSCT术后LONIPC受体行肺移植治疗的研究, 就HSCT术后肺移植手术适应证及时机、肺移植术后血液肿瘤的复发及感染并发症、肺移植术后的HSCT受体移植物存活率等方面进行总结。
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关键词:
- 异基因造血干细胞移植 /
- 迟发型非感染性肺部并发症 /
- 肺移植 /
- 慢性移植物抗宿主病 /
- 血液肿瘤 /
- 终末期肺病
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