ABO血型不相容器官移植的研究趋势与展望——文献计量分析

Research trends and prospects of ABO-incompatible organ transplantation: a bibliometric analysis

  • 摘要:
    目的 通过系统性分析ABO血型不相容(ABOi)器官移植相关研究文献,探讨该领域研究的热点与趋势。
    方法 应用CiteSpace软件对2013年1月1日至2023年12月31日间中国知网、维普网、万方数据和Web of Science核心合集数据库中收录的ABOi器官移植相关文献,清洗后进行可视化分析,包括文献发表量、发文作者、发文国家、发文机构和关键词等。
    结果 共纳入有效外文作者发表文献588篇和有效中文作者发表文献85篇。自2021年起国外文献发表量呈下降趋势,而国内文献发表量则总体呈现波动性上升。中国发文量排名前2的核心作者为王毅、朱志军;外文发文量排名前3的核心作者依次是Nakatani Tatsuya、Tanabe Kazunari、Uchida Junji。国内发文最活跃的机构为华中科技大学,其后依次是浙江大学和四川大学,相关机构间的合作密切程度相对不足。国外发文量最多的机构依次为韩国蔚山大学、首尔国立大学和日本东京女子医科大学。英文文献发文量排名前3的国家依次为日本、韩国、美国,中国位列第5。关键词聚类分析显示,国内外研究焦点主要集中在ABOi器官移植、冷沉淀、肾移植、肝移植、血型抗原检测技术、移植术后并发症等9个主题群。
    结论 目前ABOi器官移植领域的研究主要集中在肾移植和肝移植,呈现出整体向好的发展态势,未来通过加强国际合作、扩大研究投入及推广先进技术应用等手段,有望进一步促进该领域的发展。

     

    Abstract:
    Objective To systematically analyze the literature on ABO-incompatible (ABOi) organ transplantation and explore the research hotspots and trends in this field.
    Methods CiteSpace software was used for visual analysis of ABOi organ transplantation literature collected from the China National Knowledge Infrastructure, VIP web, Wanfang Data, and the Web of Science Core Collection database from January 1, 2013 to December 31, 2023 after cleaning, including the volume of literature published, authors, countries, institution and keywords.
    Results A total of 588 valid foreign-language author publications and 85 valid Chinese-language author publications were included. Since 2021, the volume of foreign literature publications has shown a downward trend, while the volume of domestic literature published has generally shown a upward trend. The top two core Chinese authors are Wang Yi and Zhu Zhijun; the top three core authors in foreign literature are Nakatani Tatsuya, Tanabe Kazunari, and Uchida Junji. The most active institution in China is Huazhong University of Science and Technology, followed by Zhejiang University and Sichuan University, with relatively insufficient closeness in cooperation between related institutions. The institutions with the most publications abroad are Ulsan University, Seoul National University and Tokyo Women's Medical University in Japan. The top three countries in English-language literature publications are Japan, Republic Korea, and the United States, and China ranked 5th. Keyword cluster analysis shows that the research focus of at home and abroad is mainly on nine topic clusters including ABOi organ transplantation, cryoprecipitation, kidney transplantation, liver transplantation, blood type antigen detection technology and post-transplant complications.
    Conclusions At present, The research in the field of ABOi organ transplantation is mainly concentrated on kidney transplantation and liver transplantation, showing an overall positive development trend. In the future, it is expected to further promote development of this field by strengthening international cooperation, expanding research investment and promoting the application of advanced technologies.

     

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