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免疫细胞功能状态量化检测评估与临床应用专家共识

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文章导航 > 器官移植  > 2024 >  15(4): 548-557
中国医疗保健国际交流促进会肝脏移植学分会, 中国医疗保健国际交流促进会肾脏移植学分会, 中国医药生物技术协会生物诊断技术分会, 等. 免疫细胞功能状态量化检测评估与临床应用专家共识[J]. 器官移植, 2024, 15(4): 548-557. doi: 10.3969/j.issn.1674-7445.2024078
引用本文: 中国医疗保健国际交流促进会肝脏移植学分会, 中国医疗保健国际交流促进会肾脏移植学分会, 中国医药生物技术协会生物诊断技术分会, 等. 免疫细胞功能状态量化检测评估与临床应用专家共识[J]. 器官移植, 2024, 15(4): 548-557. doi: 10.3969/j.issn.1674-7445.2024078
shu
China International Exchange and Promotive Association for Medical and Health Care (CPAM), Society of Liver Transplantation，Society of Kidney Transplantation; China Medicinal Biotech Association（CMBA）, Society of Biological Diagnostics, et al. Expert Consensus on quantify monitoring and assessment of immune cell function status and clinical application[J]. ORGAN TRANSPLANTATION, 2024, 15(4): 548-557. doi: 10.3969/j.issn.1674-7445.2024078
Citation: China International Exchange and Promotive Association for Medical and Health Care (CPAM), Society of Liver Transplantation，Society of Kidney Transplantation; China Medicinal Biotech Association（CMBA）, Society of Biological Diagnostics, et al. Expert Consensus on quantify monitoring and assessment of immune cell function status and clinical application[J]. ORGAN TRANSPLANTATION, 2024, 15(4): 548-557. doi: 10.3969/j.issn.1674-7445.2024078
shu

免疫细胞功能状态量化检测评估与临床应用专家共识

doi: 10.3969/j.issn.1674-7445.2024078

  • 100020　北京，首都医科大学附属北京朝阳医院

基金项目: 国家自然科学基金（82370665）；北京市自然科学基金（7232068、7232065）
详细信息
    通讯作者:

    贺强，Email： heqiang349@sina.com

    李先亮，Email： lixianliangbjcy@126.com

  • 中图分类号: R617, R392.4

Expert Consensus on quantify monitoring and assessment of immune cell function status and clinical application

More Information
    Corresponding author: He Qiang, Beijing Chaoyang Hospital of Capital Medical University, Beijing 100020, China, Email: heqiang349@sina.com; Li Xianliang, Beijing Chaoyang Hospital of Capital Medical University, Beijing 100020, China, Email: lixianliangbjcy@126.com

    摘要
  • 摘要: 免疫系统是维持机体器官功能健康和预防疾病的重要保障，免疫健康管理和疾病免疫治疗目标是恢复免疫系统的正常功能状态。免疫学领域研究解决了如何抑制或提高免疫状态的技术性难题，随之带来亟需回答的问题是如何全面地检测和量化评估免疫状态，这是下一个挑战，目前国际上尚无成熟解决方案。免疫状态量化检测与可视化评估对疾病防控、亚健康状态管理和疾病免疫治疗均具有重要意义。本专家共识针对正常免疫状态定义和免疫细胞功能状态（免疫力）全面量化评估及可视化评分技术手段等问题进行了初步讨论，提出了正常免疫状态相关的基础概念和思考，探讨免疫细胞功能状态量化检测评估方向和原则，并以此为契机，推动免疫力解码以及免疫健康领域基础课题和临床试验的深入研究。

     

    Abstract: The immune system is the important guarantee for maintaining the health of organ function and preventing diseases. The goal of immune health management and immune treatment is to restore the normal function of the immune system. The technical problems of how to inhibit or enhance the immune status has been solved in the field of immunology, but how to comprehensively detect and quantitatively evaluate the immune status is still a challenge. There is no mature solution at present. The quantification detection and visualization evaluation of immune status are of great significance for disease prevention and control, sub-health status management, and immune treatment. This expert consensus has carried out preliminary discussions on the definition of normal immune status and the comprehensive quantitative evaluation and visual scoring techniques of immune cell function status (immune function), put forward the basic concepts and thinking related to normal immune status, discussed the direction and principles of quantitative detection and evaluation of immune cell function status, and taken this as an opportunity to promote the decoding of immunity and the study of basic and clinical trials in the field of immune health.

     

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  • FIG. 3250.  FIG. 3250.

    FIG. 3250..  FIG. 3250.

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    图  1  免疫力评分体系评分尺

    注：0分为免疫平衡状态，负分为免疫抑制，正分为免疫激活。

    Figure  1.  Scoring scale for immune scoring system

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    图  2  过敏和自身免疫性疾病的免疫细胞功能状态量化评估指导治疗方向选择

    Figure  2.  Quantitative evaluation of immune cell function status in allergies and autoimmune diseases guides the selection of treatment directions

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  • 收稿日期:  2024-02-27
  • 网络出版日期:  2024-06-26
  • 刊出日期:  2024-07-15

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