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供肝保存液的演变和革新

喻国涛, 尹燕锋, 颜春涛, 等. 供肝保存液的演变和革新[J]. 器官移植, 2024, 15(1): 131-137. doi: 10.3969/j.issn.1674-7445.2023165
引用本文: 喻国涛, 尹燕锋, 颜春涛, 等. 供肝保存液的演变和革新[J]. 器官移植, 2024, 15(1): 131-137. doi: 10.3969/j.issn.1674-7445.2023165
Yu Guotao, Yin Yanfeng, Yan Chuntao, et al. Evolution and innovation of preservation fluid for donor liver[J]. ORGAN TRANSPLANTATION, 2024, 15(1): 131-137. doi: 10.3969/j.issn.1674-7445.2023165
Citation: Yu Guotao, Yin Yanfeng, Yan Chuntao, et al. Evolution and innovation of preservation fluid for donor liver[J]. ORGAN TRANSPLANTATION, 2024, 15(1): 131-137. doi: 10.3969/j.issn.1674-7445.2023165

供肝保存液的演变和革新

doi: 10.3969/j.issn.1674-7445.2023165
基金项目: 国家自然科学基金(82060436);云南省科学技术厅中青年学术和技术带头人后备人才项目(202205AC160089);云南省科学技术厅重大科技专项项目(202302AA310018);昆明医科大学研究生创新基金(2023S397)
详细信息
    作者简介:
    通讯作者:

    胡宗强(ORCID 0000-0002-7927-7007),博士,主任医师,研究方向为肝病基础研究与临床应用,Email:2509484088@qq.com

  • 中图分类号: R617, R575

Evolution and innovation of preservation fluid for donor liver

More Information
  • 摘要: 器官保存液能够改善移植物冷缺血损伤和维持移植物良好的功能。目前,如何减少供肝在冷缺血期间引起的一系列损伤,改善和提高移植物的保存质量,是目前该领域研究的热点和难点。现阶段,临床上的保存液仍未达到理想的保存效果,尤其是对于边缘供器官的保护作用不尽如人意。在当今供者极度匮乏的情况下,为了改善移植物免受冷缺血损伤,其关键要素仍然是寻求最佳的供肝保存方案。本文总结了供肝在冷缺血期间的损伤机制,保存液的分类及供肝保存液的演变历程,探讨了供肝保存液的发展方向及面临的困境,为供肝保存液的研发提供新思路和参考。

     

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出版历程
  • 收稿日期:  2023-08-25
  • 录用日期:  2023-11-22
  • 网络出版日期:  2023-11-29
  • 刊出日期:  2024-01-11

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