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高危急性髓系白血病异基因造血干细胞移植后复发的防治

王佳琦, 盛新歌, 马志豪, 等. 高危急性髓系白血病异基因造血干细胞移植后复发的防治[J]. 器官移植, 2023, 14(3): 364-370. doi: 10.3969/j.issn.1674-7445.2023.03.007
引用本文: 王佳琦, 盛新歌, 马志豪, 等. 高危急性髓系白血病异基因造血干细胞移植后复发的防治[J]. 器官移植, 2023, 14(3): 364-370. doi: 10.3969/j.issn.1674-7445.2023.03.007
Wang Jiaqi, Sheng Xinge, Ma Zhihao, et al. Prevention and treatment of high-risk acute myeloid leukemia recurrence after allogeneic hematopoietic stem cell transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(3): 364-370. doi: 10.3969/j.issn.1674-7445.2023.03.007
Citation: Wang Jiaqi, Sheng Xinge, Ma Zhihao, et al. Prevention and treatment of high-risk acute myeloid leukemia recurrence after allogeneic hematopoietic stem cell transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(3): 364-370. doi: 10.3969/j.issn.1674-7445.2023.03.007

高危急性髓系白血病异基因造血干细胞移植后复发的防治

doi: 10.3969/j.issn.1674-7445.2023.03.007
基金项目: 

福建省科技计划项目引导性项目 2019D009

厦门市医疗卫生厅指导项目 3502Z20199174

详细信息
    作者简介:
    通讯作者:

    鹿全意(ORCID:0000-0001-5133-720X),博士,主任医师,博士研究生导师,研究方向为血液内科学,Email:quanyilu@hotmail.com

  • 中图分类号: R617, R552

Prevention and treatment of high-risk acute myeloid leukemia recurrence after allogeneic hematopoietic stem cell transplantation

More Information
  • 摘要: 急性髓系白血病(AML)是一组高度异质性的克隆性疾病,化学药物治疗和造血干细胞移植均为治疗AML的方法。对于高危AML患者而言,异基因造血干细胞移植为治疗该疾病的有效手段,但部分AML患者造血干细胞移植后仍可能面临疾病复发的问题,大多数复发患者再行化学药物治疗、二次移植等的效果不佳,是导致患者异基因造血干细胞移植后死亡的主要原因。因此,加强对异基因造血干细胞移植后AML患者的随访,并采取一些合适的手段预防移植后复发显得尤为重要。本文就高危AML患者异基因造血干细胞移植后复发的监测、药物治疗和细胞治疗进行综述,以期为改善高危AML患者异基因造血干细胞移植预后提供参考。

     

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  • 收稿日期:  2022-11-01
  • 刊出日期:  2023-05-15

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