超声造影定量参数在评估脑死亡器官捐献供肝中的应用价值

任秀昀; 高农; 潘宜鹏; 吕发勤; 李威

doi:10.3969/j.issn.1674-7445.2020.05.014

超声造影定量参数在评估脑死亡器官捐献供肝中的应用价值

Application value of quantitative parameters of contrast-enhanced ultrasound in evaluating donor liver from donation after brain death

摘要

摘要:
目的探讨超声造影（CEUS）定量参数在评估脑死亡器官捐献（DBD）供肝中的应用价值。
方法回顾性分析25例DBD供肝和10例健康成人肝脏的临床资料。收集DBD供肝组和对照组的CEUS检查情况，参数包括曲线下面积（AUC）、峰值强度（I_max）、达峰时间（TTP）、平均渡越时间（mTT）等。
结果 DBD供肝组的25例中，23例为正常增强模式，另2例为异常增强模式。与对照组比较，DBD供肝组的AUC、I_max、mTT值均明显降低（均为P＜0.05）。
结论 CEUS定量参数是评估DBD供肝微灌注的有效指标。

Abstract:
Objective To evaluate the application value of quantitative parameters of contrast-enhanced ultrasound (CEUS) in evaluating the donor liver from donation after brain death (DBD).
Methods Clinical data of 25 DBD donor livers and 10 healthy adult livers were retrospectively analyzed. CEUS examinations of DBD donor livers and healthy livers were collected. Quantitative parameters included the area under curve (AUC), maximum intensity (I_max), time to peak (TTP) and mean transit time (mTT), etc.
Results Among 25 cases of DBD donor livers, 23 cases showed normal enhancement pattern, and the other 2 cases presented with abnormal enhancement pattern. Compared with the control group, the AUC, I_max and mTT values of DBD donor livers were significantly decreased (all P < 0.05).
Conclusions CEUS quantitative parameters can be effective means to evaluate the micro-perfusion of DBD donor livers.

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