Abstract: In order to further improve big data's communication and cooperative research on liver transplantation, Department of Hepatic Surgery and Liver Transplantation Center of the Third Affiliated Hospital of Sun Yat-sen University compiled the standard data set for liver transplantation, under the guidance and support of the relevant chapters and groups of the Chinese Medical Association and the Chinese Medical Doctor Association, combined domestic and foreign information standards with guidelines, data specifications and expert consensus in related fields, and at the same time, taking into account the filling needs of systems such as liver transplantation registration in China. This work is in order to promote the standardization of information in the field of liver transplantation, improve the quality of clinical information resources collection, and help to improve the clinical diagnosis, treatment and scientific research level of liver transplantation.