亲属活体供肾肾体积与受体体表面积比值对早期移植肾功能的影响

Effect of the ratio of living related donor renal volume to recipient body surface area on early function of transplanted kidney

    摘要
  • 摘要:
      目的  探讨亲属活体供肾肾体积（RV）与受体体表面积（BSA）比值（RV/BSA）与术后早期移植肾功能的关系。
      方法  回顾性分析行亲属活体肾移植术的120对供、受体的临床资料。根据RV/BSA将受体分为A组（RV/BSA < 65.33 mL/m2），B组（RV/BSA为65.33~76.49 mL/m2），C组（RV/BSA为76.50~96.96 mL/m2），D组（RV/BSA > 96.96 mL/m2）。比较4组受体术后估算肾小球滤过率（eGFR），分析RV/BSA与受体术后6、12个月eGFR的相关性。
      结果  A组术后6个月eGFR明显低于B组、C组和D组（t=2.313，2.947，5.903；均为P < 0.05）。A组术后12个月eGFR亦明显低于B组、C组和D组（t=2.189，2.433，2.909；均为P < 0.05）。RV/BSA与受体术后6、12个月的eGFR均存在相关性（均为P < 0.05）。
      结论  RV/BSA与亲属活体肾移植术后早期移植肾功能密切相关。

     

    Abstract:
      Objective   To investigate the relationship between the ratio of living related donor renal volume (RV) to recipient body surface area (BSA) (RV/BSA) and early postoperative function of transplanted kidney.
      Methods   Clinical data of 120 pairs of donors and recipients undergoing living related renal transplantation were retrospectively analyzed. According to the RV/BSA ratio, the recipients were divided into group A (RV/BSA < 65.33 mL/m2), group B (RV/BSA 65.33~76.49 mL/m2), group C (RV/BSA 76.50~96.96 mL/m2) and group D (RV/BSA > 96.96 mL/m2). The postoperative estimated glomerular filtration rate (eGFR) of recipients was compared among 4 groups. The correlation between the RV/BSA and eGFR of recipients at postoperative 6 and 12 months was analyzed.
      Results   The eGFR at postoperative 6 month in group A was significantly lower than that in groups B, C and D (t=2.313, 2.947, 5.903; all P < 0.05). The eGFR at postoperative 12 month in group A was also significantly lower than that in groups B, C and D (t=2.189, 2.433, 2.909; all P < 0.05). The RV/BSA was significantly correlated with the eGFR of recipients at postoperative 6 and 12 months (all P < 0.05).
      Conclusions  RV/BSA is intimately correlated with the early function of transplanted kidney after living related renal transplantation.

     

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