Objective  To explore treatment methods of donor kidney with single calculus in living renal transplantation and their effect.

  Methods  The treatment experience of donor kidneys with unilateral renal calculus in living renal transplantation of 3 cases was summarized, which were diagnosed before operation. The kidney with renal calculus was excised as the donor kidney; ureteroscopic lithotomy was conducted in vitro, and then renal transplantation was performed by routine operation.

  Results  There was no early complication such as delayed graft function and acute rejection in 3 recipients after operation. Three pairs of donors and recipients were followed up for 34, 45 and 62 months respectively. The color Doppler ultrasound examination of urinary system after renal transplantation showed that, new renal calculus and urinary tract obstruction did not occur in donor's preserved kidneys and recipient's transplant kidneys. Renal function of all donors and recipients was good. Three donors were followed up until now, and no abnormal urine routine was discovered. One recipient developed IgA nephropathy, which was considered to be recurrent nephropathy and had nothing to do with renal calculus.

  Conclusions  The donor kidney with single calculus in living renal transplantation can be treated effectively by ureteroscopic lithotomy in vitro after donor kidneys are excised.