民用航空超长距离转运供肺肺移植(附6例报告)

Ultra-long distance transport of donor lung for lung transplantation by civil aviation: a report of 6 cases

  • 摘要:
      目的  探讨应用民用航空超长距离转运心脏死亡器官捐献(DCD)或脑死亡器官捐献(DBD)供肺进行肺移植的可行性。
      方法  回顾性分析2015年2月至3月在南京医科大学附属无锡人民医院应用民用航空超长距离转运供肺施行肺移植手术的6例患者的临床资料。
      结果  供体6例, 为DCD或DBD供体。供肺从取出转运至肺移植手术室共耗时5.0~8.5 h, 其中含飞行时间2.0~3.0 h (里程>1 500 km)。受者接受序贯式双肺移植5例, 右单肺移植1例。手术过程顺利, 肺冷缺血时间7~12 h。受者术后接受呼吸机辅助呼吸, 于术后2~4 d脱机。截止至投稿日, 6例受者均恢复良好。
      结论  使用DCD或者DBD的肺移植供体行序贯式双肺移植手术, 若供、受体所在移植单位的两个城市间有直达航班, 且飞行时间在3.0 h内, 长距离转运是可行的。

     

    Abstract:
      Objective  To explore the feasibility of ultra-long distance transport of lung from donation after cardiac death (DCD) or donation after brain death (DBD) by civil aviation for lung transplantation.
      Methods  Clinical data of 6 cases with lung transplantation through ultra-long distance transport of lung from donors by civil aviation in Wuxi People's Hospital Affiliated to Nanjing Medical University from February to March in 2015 were analyzed retrospectively.
      Results  There were 6 donors who were DBD or DCD. It spent 5.0~8.5 h from lung removal, transport to lung transplantation in the operation room, including 2.0~3.0 h (mileage>1 500 km) for flight. Five cases received sequential double lung transplantation. One case received right single lung transplantation. The operation was conducted successfully, with the lung's cold ischemia time of 7-12 h. After operation, all patients received ventilator assisted breathing, and suspended after 2-4 d. As of the date of submission, 6 cases recovered well.
      Conclusions  Long distance transport is feasible in the case of conducting sequential double lung transplantation with donor lung from DCD or DBD, if there are direct flights between the two cities of the donor and recipient, and the flight time is within 3 h.

     

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