肺移植术后慢性移植肺失功诊治专家共识(2025版)

Expert consensus on diagnosis and treatment of chronic lung allograft dysfunction after lung transplantation (2025 edition)

  • 摘要: 肺移植是治疗终末期肺疾病的有效手段。近年来,我国接受肺移植的患者数量逐年增加,然而慢性移植肺失功作为肺移植主要的远期并发症,仍是影响移植受者长期生存的重要因素。为推动我国肺移植事业的发展,同时为患者提供全面、安全、科学、规范的诊治,中华医学会器官移植学分会肺移植学组召集具有肺移植资质医疗机构的肺移植领域专家广泛征求意见,并按照循证医学的原则,以当前已发表的中、英文最佳证据为依据,最终制定本共识。旨在最大程度解决肺移植术后慢性移植肺失功诊治过程中可能出现的问题,为术后慢性移植肺失功诊治工作者提供科学、标准的诊治方案。

     

    Abstract: Lung transplantation serves as an effective therapeutic option for end-stage pulmonary diseases. In recent years, the number of patients receiving lung transplantation in China has increased year by year. Nevertheless, chronic lung allograft dysfunction (CLAD), a major long-term complication following lung transplantation, remains a critical factor impairing the long-term survival of transplant recipients. To advance the development of lung transplantation in China and deliver comprehensive, safe, scientific and standardized diagnosis and treatment for relevant patients, the Lung Transplantation Group of Branch of Organ Transplantation of Chinese Medical Association invited thoracic surgery specialists from qualified lung transplant centers to collect extensive expert opinions. In accordance with evidence-based medicine principles and based on best available published Chinese and English clinical evidence available to date, this consensus has been formulated. It aims to resolve challenging issues in the diagnosis and treatment of post-transplant CLAD and to provide standardized clinical protocols for clinicians engaged in this field.

     

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