Abstract:
Objective To summarize the clinical experience of the first case of sulbactam-durlobactam treatment for extensively drug-resistant Acinetobacter baumannii infection after lung transplantation in China.
Methods A retrospective analysis was conducted on a case of a patient with severe chronic obstructive pulmonary disease who received sulbactam-durlobactam treatment after lung transplantation.
Results A 68-year-old male patient with a history of drug-resistant Acinetobacter baumannii infection before surgery, experienced worsening infection and impaired renal function after lung transplantation, with sputum culture showing extensively drug-resistant Acinetobacter baumannii. After receiving combination treatment with sulbactam-durlobactam and meropenem, the infection was controlled, and the function of the transplanted lung was restored.
Conclusions Sulbactam-durlobactam has potential therapeutic value for extensively drug-resistant Acinetobacter baumannii infection after lung transplantation and provides a new strategy for clinical practice.
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