Abstract: Liver transplantation is an effective treatment for end-stage liver disease in children, and its clinical efficacy has been validated. Split liver transplantation can effectively expand the donor liver pool for children. Split liver transplantation for children has specific clinical characteristics and principles. Establishing technical operation specifications for pediatric split liver transplantation plays a significant role in improving clinical efficacy. In this article, clinical practice guidelines on pediatric split liver transplantation was established in the aspect of donor and donor liver evaluation, donor-recipient matching, and ductal segmentation and reconstruction of donor liver, aiming to standardize the technical process, optimize surgical procedures, reduce the incidence of complications of split liver transplantation for children, further promoting rapid development of pediatric split liver transplantation in China.