Tan Shuncheng, Cui Jianchun, Sun Xun, et al. Exploration on the learning curve of robotic-assisted kidney transplantation[J]. ORGAN TRANSPLANTATION, 2024, 15(6): 928-934. DOI: 10.3969/j.issn.1674-7445.2024110
Citation: Tan Shuncheng, Cui Jianchun, Sun Xun, et al. Exploration on the learning curve of robotic-assisted kidney transplantation[J]. ORGAN TRANSPLANTATION, 2024, 15(6): 928-934. DOI: 10.3969/j.issn.1674-7445.2024110

Exploration on the learning curve of robotic-assisted kidney transplantation

More Information
  • Corresponding author:

    Sun Xun, Email: 769602063@qq.com

  • Received Date: May 26, 2024
  • Available Online: August 21, 2024
  • Objective 

    To explore the learning curve of robotic-assisted kidney transplantation (RAKT).

    Methods 

    The clinical data of 96 consecutive RAKT patients performed by the same surgical team were retrospectively analyzed. The arterial anastomosis time, venous anastomosis time, ureteral anastomosis time, hospital stay, and blood loss were selected as evaluation indicators. The learning curve of RAKT was analyzed using the cumulative sum (CUSUM), and the curve was divided into the learning improvement stage and the proficient mastery stage according to the learning curve. The learning curve was verified by comparing the general data and surgical data of patients in different learning stages, and the clinical efficacy of each stage was analyzed.

    Results 

    The optimal fitting equation of the learning curve reached its peak at the 33rd case, which was the minimum number of surgeries required to master RAKT. There was no statistically significant difference in age, gender, dialysis type, previous abdominal surgery history, number of donor renal arteries, and preoperative serum creatinine between the learning improvement group and the proficient mastery group (all P>0.05). Compared with the learning improvement stage, the body mass index (BMI) was higher, and the number of right donor kidney was increased compared to the left donor kidney in the proficient mastery stage (both P<0.05). There were no significant differences in arterial anastomosis time, ureteral anastomosis time, postoperative serum creatinine, and complications between the two groups (all P>0.05). The iliac vessel dissection time, warm ischemia time, venous anastomosis time, blood loss, and hospital stay in the proficient mastery stage were superior to those in the learning improvement stage, with statistically significant differences (all P<0.05).

    Conclusions 

    RAKT requires at least 33 cases to cross the learning curve. There is no difference in complications and recovery of transplant renal function between the learning improvement stage and the proficient mastery stage.

  • [1]
    魏勇, 沈露明, 朱辰, 等. 单一术者机器人辅助单孔腹腔镜前列腺癌根治术学习曲线分析[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(1): 30-35. DOI: 10.3877/cma.j.issn.1674-3253.2023.01.007.

    WEI Y, SHEN LM, ZHU C, et al. Analysis of single port robot-assisted laparoscopic prostatectomy curve of one single surgeon[J/OL]. Chin J Endourol (Electr Edit), 2023, 17(1): 30-35. DOI: 10.3877/cma.j.issn.1674-3253.2023.01.007.
    [2]
    程强, 高帆, 陈文政, 等. 达芬奇机器人全腔内原位新膀胱术的CUSUM法学习曲线分析[J]. 微创泌尿外科杂志, 2023, 12(6): 365-369. DOI: 10.19558/j.cnki.10-1020/r.2023.06.002.

    CHENG Q, GAO F, CHEN WZ, et al. Analysis of CUSUM learning curve of robotic intracorporeal Studer's orthotopic neobladder[J]. J Minim Invasive Urol, 2023, 12(6): 365-369. DOI: 10.19558/j.cnki.10-1020/r.2023.06.002.
    [3]
    LEE MR, LI WM, LI CC, et al. Cumulative sum analysis of the learning curve of laparoendoscopic single-site robot-assisted radical prostatectomy[J]. Asian J Surg, 2023, 46(9): 3614-3619. DOI: 10.1016/j.asjsur.2023.02.035.
    [4]
    AL-NADER M, RADTKE JP, PÜLLEN L, et al. Cumulative sum analysis (CUSUM) for evaluating learning curve (LC) of robotic-assisted laparoscopic partial nephrectomy (RALPN)[J]. J Robot Surg, 2023, 17(5): 2089-2098. DOI: 10.1007/s11701-023-01620-z.
    [5]
    方昌华, 杜霖, 陈鑫楠, 等. 以累积和分析法研究保留耻骨后间隙机器人辅助根治性前列腺切除术的学习曲线[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(4): 319-325. DOI: 10.3877/cma.j.issn.1674-3253.2023.04.002.

    FANG CH, DU L, CHEN XN, et al. Analysis of learning curve of retzius-sparing robot-assisted laparoscopic radical prostatectomy by cumulative summation analysis[J/OL]. Chin J Endourol (Electr Edit), 2023, 17(4): 319-325. DOI: 10.3877/cma.j.issn.1674-3253.2023.04.002.
    [6]
    CENTONZE L, BELLA CD, GIACOMONI A, et al. Robotic versus laparoscopic donor nephrectomy: a retrospective bicentric comparison of learning curves and surgical outcomes from 2 high-volume European centers[J]. Transplantation, 2023, 107(9): 2009-2017. DOI: 10.1097/TP.0000000000004618.
    [7]
    GIULIANOTTI P, GORODNER V, SBRANA F, et al. Robotic transabdominal kidney transplantation in a morbidly obese patient[J]. Am J Transplant, 2010, 10(6): 1478-1482. DOI: 10.1111/j.1600-6143.2010.03116.x.
    [8]
    MENON M, SOOD A, BHANDARI M, et al. Robotic kidney transplantation with regional hypothermia: a step-by-step description of the Vattikuti Urology Institute-Medanta technique (IDEAL phase 2a)[J]. Eur Urol, 2014, 65(5): 991-1000. DOI: 10.1016/j.eururo.2013.12.006.
    [9]
    SPAGGIARI M, PETROCHENKOV E, GRUESSNER A, et al. Robotic kidney transplantation from deceased donors: a single-center experience[J]. Am J Transplant, 2023, 23(5): 642-648. DOI: 10.1016/j.ajt.2023.02.016.
    [10]
    TERRITO A, BAJEOT AS, MESNARD B, et al. Open versus robotic-assisted kidney transplantation: a systematic review by the European Association of Urology (EAU) - Young Academic Urologists (YAU) Kidney Transplant Working Group[J]. Actas Urol Esp, 2023, 47(8): 474-487. DOI: 10.1016/j.acuroe.2023.03.003.
    [11]
    CAMPI R, PECORARO A, MARZI VL, et al. Robotic versus open kidney transplantation from deceased donors: a prospective observational study[J]. Eur Urol Open Sci, 2022, 39: 36-46. DOI: 10.1016/j.euros.2022.03.007.
    [12]
    TERRITO A, MOTTRIE A, ABAZA R, et al. Robotic kidney transplantation: current status and future perspectives[J]. Ital J Urol Nephrol, 2017, 69(1): 5-13. DOI: 10.23736/S0393-2249.16.02856-3.
    [13]
    GANPULE A, PATIL A, SINGH A, et al. Robotic-assisted kidney transplant: a single center experience with median follow-up of 2.8years[J]. World J Urol, 2020, 38(10): 2651-2660. DOI: 10.1007/s00345-019-02934-0.
    [14]
    LEE SD, RAWASHDEH B, MCCRACKEN EKE, et al. Robot-assisted kidney transplantation is a safe alternative approach for morbidly obese patients with end-stage renal disease[J]. Int J Med Robot, 2021, 17(5): e2293. DOI: 10.1002/rcs.2293.
    [15]
    HERRERA S, CARBONELL I, COFAN F, et al. Impact of robotic-assisted kidney transplantation on post-transplant infections: a case-control study[J]. World J Urol, 2023, 41(10): 2847-2853. DOI: 10.1007/s00345-023-04484-y.
    [16]
    PECORARO A, BASILE G, GALLIOLI A, et al. Penetrance of robot-assisted kidney transplantation in surgical practice at referral European transplant centres: an audit within the ERUS-RAKT working group[J]. Eur Urol Open Sci, 2024, 62: 16-18. DOI: 10.1016/j.euros.2024.01.016.
    [17]
    王昕凝, 祖强, 祝强, 等. 机器人辅助腹腔镜肾移植术1例报道并文献复习[J]. 微创泌尿外科杂志, 2018, 7(3): 159-162. DOI: 10.19558/j.cnki.10-1020/r.2018.03.004.

    WANG XN, ZU Q, ZHU Q, et al. Surgical outcomes of robotic-assisted kidney transplantation in end-stage renal disease treatment (1 case report)[J]. J Minim Invasive Urol, 2018, 7(3): 159-162. DOI: 10.19558/j.cnki.10-1020/r.2018.03.004.
    [18]
    刘光香, 庄君龙, 邓永明, 等. 机器人辅助腹腔镜亲属供肾肾移植取-植一体术初步经验[J]. 中华外科杂志, 2023, 61(1): 66-68. DOI: 10.3760/cma.j.cn112139-20220715-00314.

    LIU GX, ZHUANG JL, DENG YM, et al. Preliminary experience of robot-assisted laparoscopic kidney transplantation from relatives[J]. Chin J Surg, 2023, 61(1): 66-68. DOI: 10.3760/cma.j.cn112139-20220715-00314.
    [19]
    谭顺成, 崔建春, 宋永琳, 等. 机器人辅助腹腔镜肾移植术初步经验(附22例报告)[J]. 微创泌尿外科杂志, 2021, 10(3): 157-162. DOI: 10.19558/j.cnki.10-1020/r.2021.03.003.

    TAN SC, CUI JC, SONG YL, et al. Preliminary experience of robot-assisted laparoscopic kidney transplantation(report of 22 cases)[J]. J Minim Invasive Urol, 2021, 10(3): 157-162. DOI: 10.19558/j.cnki.10-1020/r.2021.03.003.
    [20]
    姜玲, 甘晓琴, 裴皓玉, 等. 机器人辅助腹腔镜亲属肾移植术4例手术配合[J]. 现代医药卫生, 2023, 39(2): 354-357. DOI: 10.3969/j.issn.1009-5519.2023.02.038.

    JIANG L, GAN XQ, PEI HY, et al. Surgical cooperation in 4 cases of robot assisted laparoscopic relative kidney transplantation[J]. J Mod Med Health, 2023, 39(2): 354-357. DOI: 10.3969/j.issn.1009-5519.2023.02.038.
    [21]
    张明晓, 丁振山, 王建峰, 等. 机器人辅助肾移植术单中心初步经验[J]. 器官移植, 2024, 15(3): 422-428. DOI: 10.3969/j.issn.1674-7445.2023261.

    ZHANG MX, DING ZS, WANG JF, et al. Preliminary experience of robot-assisted renal transplantation in a single center[J]. Organ Transplant, 2024, 15(3): 422-428. DOI: 10.3969/j.issn.1674-7445.2023261.
    [22]
    钟晓, 兰卫华, 王洛夫, 等. 机器人肾移植术围手术期疗效分析[J]. 陆军军医大学学报, 2022, 44(18): 1862-1866. DOI: 10.16016/j.2097-0927.202204035.

    ZHONG X, LAN WH, WANG LF, et al. Efficacy of robotic renal transplantation in perioperative period[J]. J Army Med Univ, 2022, 44(18): 1862-1866. DOI: 10.16016/j.2097-0927.202204035.
    [23]
    赵鉴明, 范阳, 陈欣, 等. 机器人辅助腹腔镜同种异体肾移植术的早中期结果[J]. 微创泌尿外科杂志, 2021, 10(2): 80-83. DOI: 10.19558/j.cnki.10-1020/r.2021.02.002.

    ZHAO JM, FAN Y, CHEN X, et al. Early and mid-term results of robot-assisted laparoscopic kidney transplantation[J]. J Minim Invasive Urol, 2021, 10(2): 80-83. DOI: 10.19558/j.cnki.10-1020/r.2021.02.002.
    [24]
    MODI P, RIZVI J, PAL B, et al. Laparoscopic kidney transplantation: an initial experience[J]. Am J Transplant, 2011, 11(6): 1320-1324. DOI: 10.1111/j.1600-6143.2011.03512.x.
    [25]
    AHLAWAT RK, TUGCU V, ARORA S, et al. Learning curves and timing of surgical trials: robotic kidney transplantation with regional hypothermia[J]. J Endourol, 2018, 32(12): 1160-1165. DOI: 10.1089/end.2017.0697.
    [26]
    BANSAL D, CHATURVEDI S, MAHESHWARI R, et al. Establishing a robot-assisted kidney transplant program: independent evaluation of the learning curve and surgical nuances[J]. J Endourol, 2021, 35(11): 1650-1658. DOI: 10.1089/end.2020.0923.
    [27]
    KIM HJ, JEONG W, LEE J, et al. Successful robotic kidney transplantation for surgeons with no experience in minimally invasive surgery: a single institution experience[J]. Int J Surg, 2024, 110(3): 1586-1594. DOI: 10.1097/JS9.0000000000000977.
    [28]
    GALLIOLI A, TERRITO A, BOISSIER R, et al. Learning curve in robot-assisted kidney transplantation: results from the European robotic urological society working group[J]. Eur Urol, 2020, 78(2): 239-247. DOI: 10.1016/j.eururo.2019.12.008.
    [29]
    TUĞCU V, ŞENER NC, ŞAHIN S, et al. Robot-assisted kidney transplantation: comparison of the first 40 cases of open vs robot-assisted transplantations by a single surgeon[J]. BJU Int, 2018, 121(2): 275-280. DOI: 10.1111/bju.14014.
    [30]
    TINNEY F, IVANICS T, STRACKE J, et al. Robotic-assisted versus open technique for living donor kidney transplantation: a comparison using propensity score matching for intention to treat[J]. Transplant Direct, 2022, 8(5): e1320. DOI: 10.1097/TXD.0000000000001320.
    [31]
    KULKARNI S, WEI G, JIANG W, et al. Outcomes from right versus left deceased-donor kidney transplants: a US national cohort study[J]. Am J Kidney Dis, 2020, 75(5): 725-735. DOI: 10.1053/j.ajkd.2019.08.018.
    [32]
    KISHORE TA, KURIAKOSE MJ, PATHROSE G, et al. Robotic assisted kidney transplantation in grafts with multiple vessels: single center experience[J]. Int Urol Nephrol, 2020, 52(2): 247-252. DOI: 10.1007/s11255-019-02305-z.
    [33]
    KISHORE TA, KADDU DJ, SODHI BS, et al. Robotic kidney transplant beyond the learning curve: 8-year single-center experience and matched comparison with open kidney transplant[J]. Urology, 2024, 183: 100-105. DOI: 10.1016/j.urology.2023.10.031.
    [34]
    AHLAWAT R. Robotic kidney transplantation under regional hypothermia[J]. J Endourol, 2022, 36(S2): S18-S24. DOI: 10.1089/end.2022.0362.
    [35]
    ZHANG H, ZENG J, FAN Y, et al. Continuous renal Surface Cooling Technique (CSCT) in robotic assisted kidney transplantation: technique and outcomes from a high-volume center, a prospective cohort study[J]. Int J Surg, 2024, 110(7): 4143-4150. DOI: 10.1097/JS9.0000000000001385.
    [36]
    GORAYEB-POLACCHINI FS, CALDAS HC, FERNANDES-CHARPIOT IMM, et al. Impact of cold ischemia time on kidney transplant: a mate kidney analysis[J]. Transplant Proc, 2020, 52(5): 1269-1271. DOI: 10.1016/j.transproceed.2019.12.052.
    [37]
    崔建春, 谭顺成, 宋永琳, 等. 机器人辅助肾移植术的初步体验与疗效观察[J]. 中华器官移植杂志, 2021, 42(7): 398-403. DOI: 10.3760/cma.j.cn421203-20201117-00392.

    CUI JC, TAN SC, SONG YL, et al. Preliminary experiences and curative outcomes of robot-assisted kidney transplantation[J]. Chin J Organ Transplant, 2021, 42(7): 398-403. DOI: 10.3760/cma.j.cn421203-20201117-00392.
    [38]
    CAMPI R, PECORARO A, PIRAMIDE F, et al. The ERUS course on robot-assisted kidney transplantation[J]. World J Urol, 2024, 42(1): 205. DOI: 10.1007/s00345-024-04802-y.
    [39]
    GHAZI A, SABA P, MELNYK R, et al. Utilizing 3D printing and hydrogel casting for the development of patient-specific rehearsal platforms for robotic assisted partial nephrectomies[J]. Urology, 2021, 147: 317. DOI: 10.1016/j.urology.2020.10.023.
    [40]
    LUCEREAU B, THAVEAU F, LEJAY A, et al. Learning curve of robotic-assisted anastomosis: shorter than the laparoscopic technique? an educational study[J]. Ann Vasc Surg, 2016, 33: 39-44. DOI: 10.1016/j.avsg.2015.12.001.

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