Volume 9 Issue 6
Nov.  2018
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Article Navigation >  ORGAN TRANSPLANTATION  > 2018  >  9(6): 451-455
Chen Huanwei, Luan Xiaojun, Liu Chengyang, et al. Total pancreatectomy-islet autotransplantation in treatment of chronic pancreatitis: report of one case and literature review[J]. ORGAN TRANSPLANTATION, 2018, 9(6): 451-455. doi: 10.3969/j.issn.1674-7445.2018.06.010
Citation: Chen Huanwei, Luan Xiaojun, Liu Chengyang, et al. Total pancreatectomy-islet autotransplantation in treatment of chronic pancreatitis: report of one case and literature review[J]. ORGAN TRANSPLANTATION, 2018, 9(6): 451-455. doi: 10.3969/j.issn.1674-7445.2018.06.010
shu

Total pancreatectomy-islet autotransplantation in treatment of chronic pancreatitis: report of one case and literature review

doi: 10.3969/j.issn.1674-7445.2018.06.010

  • Department of Pancreatic Surgery, the First People's Hospital of Foshan, Foshan 528000, China

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  • Corresponding author: Chen Guoqiang, Email: cgqiang@fsyyy.com
  • Received Date: 2018-08-30
    Available Online: 2021-01-19
  • Publish Date: 2018-11-15
    Abstract
  •   Objective  To evaluate the clinical efficacy of total pancreatectomy-islet autotransplantation (TP-IAT) in the treatment of chronic pancreatitis.  Methods  One patient diagnosed with refractory chronic pancreatitis complicated with multiple pseudocysts and pancreatic stones underwent TP-IAT in the First People's Hospital of Foshan. Clinical data were collected and analyzed during postoperative 3 months follow-up.  Results  The patient was well recovered after TP-IAT without complications, such as bleeding and severe hypoglycemia. Abdominal pain was completely relieved without taking analgesic drugs. During postoperative follow-up, the patient was treated with exogenous insulin, the fasting blood glucose was properly controlled and the function of islet cells was partially restored.  Conclusions  TP-IAT can not only relieve the clinical symptoms of chronic pancreatitis, but also prevent postoperative diabetes mellitus, which is an efficacious treatment of refractory chronic pancreatitis.

     

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