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肺移植术后胃肠道并发症的研究进展

严浩吉 陈蔚洋 魏桢婷 刘眉涵 邓诗扬 黄桁 姜凯元 田东

严浩吉, 陈蔚洋, 魏桢婷, 等. 肺移植术后胃肠道并发症的研究进展[J]. 器官移植, 2020, 11(6): 749-753, 764. doi: 10.3969/j.issn.1674-7445.2020.06.016
引用本文: 严浩吉, 陈蔚洋, 魏桢婷, 等. 肺移植术后胃肠道并发症的研究进展[J]. 器官移植, 2020, 11(6): 749-753, 764. doi: 10.3969/j.issn.1674-7445.2020.06.016
Yan Haoji, Chen Weiyang, Wei Zhenting, et al. Research progress on gastrointestinal complications after lung transplantation[J]. ORGAN TRANSPLANTATION, 2020, 11(6): 749-753, 764. doi: 10.3969/j.issn.1674-7445.2020.06.016
Citation: Yan Haoji, Chen Weiyang, Wei Zhenting, et al. Research progress on gastrointestinal complications after lung transplantation[J]. ORGAN TRANSPLANTATION, 2020, 11(6): 749-753, 764. doi: 10.3969/j.issn.1674-7445.2020.06.016

肺移植术后胃肠道并发症的研究进展

doi: 10.3969/j.issn.1674-7445.2020.06.016
基金项目: 

四川省医学会青年创新课题 Q18042

2019年国家级大学生创新创业训练计划 201910634061

2019年南充市校合作项目 19SXHZ0189

详细信息
    通讯作者:

    田东,男,博士,研究方向为肺移植基础与临床研究,Email:22tiandong@163.com

  • 中图分类号: R617, R574

Research progress on gastrointestinal complications after lung transplantation

More Information
  • 摘要: 由于免疫抑制和神经损伤等综合因素的影响,肺移植术后胃肠道并发症的总体发生率较高,可引起受者药物吸收障碍和慢性排斥反应。近年来,关于该并发症的研究逐渐增多,但由于各肺移植中心胃肠道并发症发病情况差异较大,临床医师对其认知并不全面。本文对肺移植术后胃肠道并发症的一般情况、常见类型以及危险因素进行了综述,旨在为肺移植术后胃肠道并发症的综合管理提供参考依据。

     

  • 表  1  肺移植术后胃肠道并发症的基本情况

    Table  1.   Basic situation of gastrointestinal complications after lung transplantation

    研究作者 年份 n 发生率[n(%)] 病死率[n(%)] 主要并发症
    Costa HF, et al[3] 2003~2016 274 49 (18) 28 (57) 肠梗阻、腹膜炎、肠穿孔
    Paul S, et al[4] 1990~2005 208 90 (43) 11 (12) 胆道疾病、结肠炎、小肠梗阻
    Smith PC, et al[5] 1988~1993 75 12 (6) 4 (33) 肠梗阻、膈疝、肠缺血
    Grass F, et al[6] 1993~2010 205 127 (62) 4 (3) GERD、结肠炎、胃瘫
    Kayawake H, et al[7] 2008~2017 160 58 (36) 2 (4) 胃瘫、GERD、结肠炎
    Timrott K, et al[8] 2000~2008 754 55 (7) 12 (22) 肠穿孔、腹膜炎、肠梗阻
    Miller CB, et al[9] 1997~2004 229 47 (21) 13 (28) 肠梗阻、消化性溃疡、急性胰腺炎
    Zevallos-Villegas A, et al[10] 2008~2015 136 17 (13) 9 (53) 胆道疾病、胃肠道出血、肠穿孔
    Lahon B, et al[11] 1988~2009 351 26 (7) 5 (19) 胆囊炎、血管炎、胃十二指肠穿孔
    Hoekstra HJ, et al[12] 1990~1999 125 12 (10) - 肠穿孔、阑尾炎、胆囊炎
    注:①-为未提及。
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出版历程
  • 收稿日期:  2020-07-15
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2021-01-19

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